| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CSNK2A1 | TCF7L2 | Ser60 | ETNQNSSsDSEAERR | phosphorylation up-regulates activity | 11711551 | SIGNOR-250964 |
| CSNK2A2 | TCF7L2 | Ser60 | ETNQNSSsDSEAERR | phosphorylation up-regulates activity | 11711551 | SIGNOR-251046 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CSNK2A1 | phosphorylation up-regulates → | TCF7L2 PSer60 | phosphorylation up-regulates → | TCF7L2 | 11711551 | SIGNOR-250964 |
| CSNK2A2 | phosphorylation up-regulates → | TCF7L2 PSer60 | phosphorylation up-regulates → | TCF7L2 | 11711551 | SIGNOR-251046 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CSNK2A1 | phosphorylation → up-regulates activity | TCF7L2 | SIGNOR-250964 |
| CSNK2A2 | phosphorylation → up-regulates activity | TCF7L2 | SIGNOR-251046 |