Entity Details

Name IKBKE_Ser418
ID Q9NQC7
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CAMK2BCYLDSer418TTENRFHsLPFSLTKphosphorylation
up-regulates activity		24614225SIGNOR-25329
IKBKBCYLDSer418TTENRFHsLPFSLTKphosphorylation
down-regulates activity		24614225SIGNOR-204716
IKK-complexCYLDSer418TTENRFHsLPFSLTKphosphorylation
down-regulates activity		15870263SIGNOR-266435
IKBKECYLDSer418TTENRFHsLPFSLTKphosphorylation
down-regulates activity		19481526SIGNOR-278311
IKBKBCYLDSer418TTENRFHsLPFSLTKphosphorylation
down-regulates activity		15870263SIGNOR-266436
CHUKCYLDSer418TTENRFHsLPFSLTKphosphorylation
down-regulates activity		24614225SIGNOR-204688
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CAMK2Bphosphorylation
up-regulates
→
CYLD
PSer418		phosphorylation
up-regulates
→		CYLD24614225SIGNOR-25329
IKBKBphosphorylation
up-regulates
→
CYLD
PSer418		phosphorylation
down-regulates
⊣		CYLD24614225SIGNOR-204716
IKK-complexphosphorylation
up-regulates
→
CYLD
PSer418		phosphorylation
down-regulates
⊣		CYLD15870263SIGNOR-266435
IKBKEphosphorylation
up-regulates
→
CYLD
PSer418		phosphorylation
down-regulates
⊣		CYLD19481526SIGNOR-278311
IKBKBphosphorylation
up-regulates
→
CYLD
PSer418		phosphorylation
down-regulates
⊣		CYLD15870263SIGNOR-266436
CHUKphosphorylation
up-regulates
→
CYLD
PSer418		phosphorylation
down-regulates
⊣		CYLD24614225SIGNOR-204688
Regulator Mechanism/Effect Target SIGNOR-ID
CAMK2Bphosphorylation
→
up-regulates activity 		CYLDSIGNOR-25329
IKBKBphosphorylation
→
down-regulates activity 		CYLDSIGNOR-204716
IKK-complexphosphorylation
→
down-regulates activity 		CYLDSIGNOR-266435
IKBKEphosphorylation
→
down-regulates activity 		CYLDSIGNOR-278311
IKBKBphosphorylation
→
down-regulates activity 		CYLDSIGNOR-266436
CHUKphosphorylation
→
down-regulates activity 		CYLDSIGNOR-204688