Entity Details

Name SIRT7
ID Q9NRC8
Role substrate
Enzymatic Domains
Deacetylase sirtuin-type 82-329
PROSITE-ProRule
View in

Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
AMPKSIRT7Thr153TLTHMSItRLHEQKLphosphorylation
down-regulates quantity by destabilization		27511885SIGNOR-275865
PRKAA1SIRT7Thr153TLTHMSItRLHEQKLphosphorylation
down-regulates quantity by destabilization		27511885SIGNOR-275864
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
AMPKphosphorylation
up-regulates
→
SIRT7
PThr153		phosphorylation
down-regulates
⊣		SIRT727511885SIGNOR-275865
PRKAA1phosphorylation
up-regulates
→
SIRT7
PThr153		phosphorylation
down-regulates
⊣		SIRT727511885SIGNOR-275864
Regulator Mechanism/Effect Target SIGNOR-ID
AMPKphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		SIRT7SIGNOR-275865
PRKAA1phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		SIRT7SIGNOR-275864