| Name | DUOX1 |
| ID | Q9NRD9 |
| Role | substrate |
| Enzymatic Domains |
EF-hand 1 815-850 PROSITE-ProRule
EF-hand 2 851-886 PROSITE-ProRule
EF-hand 3 895-930 PROSITE-ProRule
Ferric oxidoreductase 1087-1269
FAD-binding FR-type 1270-1376 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKACA | DUOX1 | Ser1217 | SHHFRRRsFRGFWLT | phosphorylation up-regulates | 19144650 | SIGNOR-183445 |
| PRKACA | DUOX1 | Ser955 | KDLCRRAsYISQDMI | phosphorylation up-regulates | 19144650 | SIGNOR-183449 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKACA | phosphorylation up-regulates → | DUOX1 PSer1217 | phosphorylation up-regulates → | DUOX1 | 19144650 | SIGNOR-183445 |
| PRKACA | phosphorylation up-regulates → | DUOX1 PSer955 | phosphorylation up-regulates → | DUOX1 | 19144650 | SIGNOR-183449 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKACA | phosphorylation → up-regulates | DUOX1 | SIGNOR-183445 |
| PRKACA | phosphorylation → up-regulates | DUOX1 | SIGNOR-183449 |