| Name | SH2B1 |
| ID | Q9NRF2 |
| Role | phosphatase |
| Enzymatic Domains |
PH 267-376
SH2 527-625 PROSITE-ProRule |
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|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SH2B1 | CD79A | – | dephosphorylation down-regulates activity | 32323266 | SIGNOR-268457 | |
| SH2B1 | CD79B | – | dephosphorylation down-regulates activity | 32323266 | SIGNOR-268458 | |
| SH2B1 | SYK | – | dephosphorylation down-regulates activity | 32323266 | SIGNOR-268445 | |
| SH2B1 | BLNK | – | dephosphorylation down-regulates activity | 32323266 | SIGNOR-268446 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| SH2B1 | dephosphorylation → down-regulates activity | CD79A | SIGNOR-268457 |
| SH2B1 | dephosphorylation → down-regulates activity | CD79B | SIGNOR-268458 |
| SH2B1 | dephosphorylation → down-regulates activity | SYK | SIGNOR-268445 |
| SH2B1 | dephosphorylation → down-regulates activity | BLNK | SIGNOR-268446 |