| Name | LATS2 |
| ID | Q9NRM7 |
| Role | substrate |
| Enzymatic Domains |
UBA 98-139 PROSITE-ProRule
Protein kinase 668-973 PROSITE-ProRule
AGC-kinase C-terminal 974-1052 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| STK3 | LATS2 | Thr1041 | EHAFYEFtFRRFFDD | phosphorylation up-regulates | 21808241 | SIGNOR-175801 |
| STK3 | LATS2 | Ser872 | HQRCLAHsLVGTPNY | phosphorylation up-regulates | 21808241 | SIGNOR-175797 |
| AURKA | LATS2 | Ser83 | ALREIRYsLLPFANE | phosphorylation up-regulates | 15147269 | SIGNOR-124830 |
| STK4 | LATS2 | Ser872 | HQRCLAHsLVGTPNY | phosphorylation up-regulates | 23431053 | SIGNOR-201298 |
| STK3 | LATS2 | Thr1041 | EHAFYEFtFRRFFDD | phosphorylation up-regulates | 23431053 | SIGNOR-201278 |
| STK4 | LATS2 | Thr1041 | EHAFYEFtFRRFFDD | phosphorylation up-regulates | 23431053 | SIGNOR-201302 |
| AURKA | LATS2 | Ser380 | ATLARRDsLQKPGLE | phosphorylation up-regulates | 21822051 | SIGNOR-175939 |
| STK4 | LATS2 | Thr1041 | EHAFYEFtFRRFFDD | phosphorylation up-regulates | 21808241 | SIGNOR-175825 |
| STK3 | LATS2 | Ser872 | HQRCLAHsLVGTPNY | phosphorylation up-regulates | 23431053 | SIGNOR-201274 |
| STK3/4 | LATS2 | – | phosphorylation up-regulates | 21808241 | SIGNOR-270218 | |
| PRKACA | LATS2 | – | phosphorylation up-regulates | 23644383 | SIGNOR-236994 | |
| STK4 | LATS2 | Ser872 | HQRCLAHsLVGTPNY | phosphorylation up-regulates | 21808241 | SIGNOR-175821 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| STK3 | phosphorylation up-regulates → | LATS2 PThr1041 | phosphorylation up-regulates → | LATS2 | 21808241 | SIGNOR-175801 |
| STK3 | phosphorylation up-regulates → | LATS2 PSer872 | phosphorylation up-regulates → | LATS2 | 21808241 | SIGNOR-175797 |
| AURKA | phosphorylation up-regulates → | LATS2 PSer83 | phosphorylation up-regulates → | LATS2 | 15147269 | SIGNOR-124830 |
| STK4 | phosphorylation up-regulates → | LATS2 PSer872 | phosphorylation up-regulates → | LATS2 | 23431053 | SIGNOR-201298 |
| STK3 | phosphorylation up-regulates → | LATS2 PThr1041 | phosphorylation up-regulates → | LATS2 | 23431053 | SIGNOR-201278 |
| STK4 | phosphorylation up-regulates → | LATS2 PThr1041 | phosphorylation up-regulates → | LATS2 | 23431053 | SIGNOR-201302 |
| AURKA | phosphorylation up-regulates → | LATS2 PSer380 | phosphorylation up-regulates → | LATS2 | 21822051 | SIGNOR-175939 |
| STK4 | phosphorylation up-regulates → | LATS2 PThr1041 | phosphorylation up-regulates → | LATS2 | 21808241 | SIGNOR-175825 |
| STK3 | phosphorylation up-regulates → | LATS2 PSer872 | phosphorylation up-regulates → | LATS2 | 23431053 | SIGNOR-201274 |
| STK4 | phosphorylation up-regulates → | LATS2 PSer872 | phosphorylation up-regulates → | LATS2 | 21808241 | SIGNOR-175821 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| STK3 | phosphorylation → up-regulates | LATS2 | SIGNOR-175801 |
| STK3 | phosphorylation → up-regulates | LATS2 | SIGNOR-175797 |
| AURKA | phosphorylation → up-regulates | LATS2 | SIGNOR-124830 |
| STK4 | phosphorylation → up-regulates | LATS2 | SIGNOR-201298 |
| STK3 | phosphorylation → up-regulates | LATS2 | SIGNOR-201278 |
| STK4 | phosphorylation → up-regulates | LATS2 | SIGNOR-201302 |
| AURKA | phosphorylation → up-regulates | LATS2 | SIGNOR-175939 |
| STK4 | phosphorylation → up-regulates | LATS2 | SIGNOR-175825 |
| STK3 | phosphorylation → up-regulates | LATS2 | SIGNOR-201274 |
| STK3/4 | phosphorylation → up-regulates | LATS2 | SIGNOR-270218 |
| PRKACA | phosphorylation → up-regulates | LATS2 | SIGNOR-236994 |
| STK4 | phosphorylation → up-regulates | LATS2 | SIGNOR-175821 |