Entity Details

Name DUSP22
ID Q9NRW4
Role phosphatase
Enzymatic Domains
Tyrosine-protein phosphatase 4-144
PROSITE-ProRule
View in

Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
DUSP22ESR1Ser118LHPPPQLsPFLQPHGdephosphorylation
down-regulates activity		17384676SIGNOR-248827
DUSP22LCK–dephosphorylation
down-regulates activity		27557500SIGNOR-277148
DUSP22STAT3–dephosphorylation
down-regulates activity		16636663SIGNOR-277149
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
DUSP22dephosphorylation
down-regulates
⊣
ESR1
PSer118		dephosphorylation
up-regulates
→		ESR117384676SIGNOR-248827
Regulator Mechanism/Effect Target SIGNOR-ID
DUSP22dephosphorylation
→
down-regulates activity 		ESR1SIGNOR-248827
DUSP22dephosphorylation
→
down-regulates activity 		LCKSIGNOR-277148
DUSP22dephosphorylation
→
down-regulates activity 		STAT3SIGNOR-277149