| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SRC | ARHGAP35 | Tyr1105 | RNEEENIySVPHDST | phosphorylation up-regulates | 9819392 | SIGNOR-61670 |
| PTPRZ1 | ARHGAP35 | Tyr1105 | RNEEENIySVPHDST | dephosphorylation down-regulates activity | 16513268 | SIGNOR-248451 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SRC | phosphorylation up-regulates → | ARHGAP35 PTyr1105 | phosphorylation up-regulates → | ARHGAP35 | 9819392 | SIGNOR-61670 |
| PTPRZ1 | dephosphorylation down-regulates ⊣ | ARHGAP35 PTyr1105 | dephosphorylation up-regulates → | ARHGAP35 | 16513268 | SIGNOR-248451 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| SRC | phosphorylation → up-regulates | ARHGAP35 | SIGNOR-61670 |
| PTPRZ1 | dephosphorylation → down-regulates activity | ARHGAP35 | SIGNOR-248451 |
