| Name | IRAK4 |
| ID | Q9NWZ3 |
| Role | substrate |
| Enzymatic Domains |
Death 20-104
Protein kinase 186-454 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| IRAK4 | IRAK4 | Thr342 | ASEKFAQtVMTSRIV | phosphorylation up-regulates activity | 17141195 | SIGNOR-151006 |
| IRAK4 | IRAK4 | Thr345 | KFAQTVMtSRIVGTT | phosphorylation up-regulates activity | 24567333 | SIGNOR-204661 |
| IRAK4 | IRAK4 | Ser346 | FAQTVMTsRIVGTTA | phosphorylation up-regulates activity | 24567333 | SIGNOR-204653 |
| IRAK4 | IRAK4 | Thr342 | ASEKFAQtVMTSRIV | phosphorylation up-regulates activity | 24567333 | SIGNOR-204657 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| IRAK4 | phosphorylation up-regulates → | IRAK4 PThr342 | phosphorylation up-regulates → | IRAK4 | 17141195 | SIGNOR-151006 |
| IRAK4 | phosphorylation up-regulates → | IRAK4 PThr345 | phosphorylation up-regulates → | IRAK4 | 24567333 | SIGNOR-204661 |
| IRAK4 | phosphorylation up-regulates → | IRAK4 PSer346 | phosphorylation up-regulates → | IRAK4 | 24567333 | SIGNOR-204653 |
| IRAK4 | phosphorylation up-regulates → | IRAK4 PThr342 | phosphorylation up-regulates → | IRAK4 | 24567333 | SIGNOR-204657 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| IRAK4 | phosphorylation → up-regulates activity | IRAK4 | SIGNOR-151006 |
| IRAK4 | phosphorylation → up-regulates activity | IRAK4 | SIGNOR-204661 |
| IRAK4 | phosphorylation → up-regulates activity | IRAK4 | SIGNOR-204653 |
| IRAK4 | phosphorylation → up-regulates activity | IRAK4 | SIGNOR-204657 |