| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GSK3B | DDIT4 | Thr23 | SPSSLPRtPTPDRPP | phosphorylation down-regulates quantity by destabilization | 23717519 | SIGNOR-279525 |
| GSK3B | DDIT4 | Thr25 | SSLPRTPtPDRPPRS | phosphorylation down-regulates quantity by destabilization | 23717519 | SIGNOR-279526 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GSK3B | phosphorylation up-regulates → | DDIT4 PThr23 | phosphorylation down-regulates ⊣ | DDIT4 | 23717519 | SIGNOR-279525 |
| GSK3B | phosphorylation up-regulates → | DDIT4 PThr25 | phosphorylation down-regulates ⊣ | DDIT4 | 23717519 | SIGNOR-279526 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| GSK3B | phosphorylation![]() down-regulates quantity by destabilization | DDIT4 | SIGNOR-279525 |
| GSK3B | phosphorylation![]() down-regulates quantity by destabilization | DDIT4 | SIGNOR-279526 |