Entity Details

Name JAK1_Tyr619
ID Q9NZJ5
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
JAK1EIF2AK3Tyr619NKVDDCNyAIKRIRLphosphorylation
up-regulates activity		25113558SIGNOR-276677
EIF2AK3EIF2AK3Tyr619NKVDDCNyAIKRIRLphosphorylation
up-regulates		17998206SIGNOR-159156
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
JAK1phosphorylation
up-regulates
→
EIF2AK3
PTyr619		phosphorylation
up-regulates
→		EIF2AK325113558SIGNOR-276677
EIF2AK3phosphorylation
up-regulates
→
EIF2AK3
PTyr619		phosphorylation
up-regulates
→		EIF2AK317998206SIGNOR-159156
Regulator Mechanism/Effect Target SIGNOR-ID
JAK1phosphorylation
→
up-regulates activity 		EIF2AK3SIGNOR-276677
EIF2AK3phosphorylation
→
up-regulates 		EIF2AK3SIGNOR-159156