| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| FGFR1 | PDP1 | Tyr94 | SILKANEySFKVPEF | phosphorylation down-regulates activity | 24962578 | SIGNOR-276640 |
| JAK2 | PDP1 | Tyr94 | SILKANEySFKVPEF | phosphorylation down-regulates activity | 24962578 | SIGNOR-276642 |
| ABL1 | PDP1 | Tyr94 | SILKANEySFKVPEF | phosphorylation down-regulates activity | 24962578 | SIGNOR-276641 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| FGFR1 | phosphorylation up-regulates → | PDP1 PTyr94 | phosphorylation down-regulates ⊣ | PDP1 | 24962578 | SIGNOR-276640 |
| JAK2 | phosphorylation up-regulates → | PDP1 PTyr94 | phosphorylation down-regulates ⊣ | PDP1 | 24962578 | SIGNOR-276642 |
| ABL1 | phosphorylation up-regulates → | PDP1 PTyr94 | phosphorylation down-regulates ⊣ | PDP1 | 24962578 | SIGNOR-276641 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| FGFR1 | phosphorylation → down-regulates activity | PDP1 | SIGNOR-276640 |
| JAK2 | phosphorylation → down-regulates activity | PDP1 | SIGNOR-276642 |
| ABL1 | phosphorylation → down-regulates activity | PDP1 | SIGNOR-276641 |