| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| LRRK2 | LARS1 | Thr293 | NIFLVAAtLRPETMF | phosphorylation down-regulates activity | 30411383 | SIGNOR-277417 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| LRRK2 | phosphorylation up-regulates → | LARS1 PThr293 | phosphorylation down-regulates ⊣ | LARS1 | 30411383 | SIGNOR-277417 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| LRRK2 | phosphorylation → down-regulates activity | LARS1 | SIGNOR-277417 |