Entity Details

Name PPARGC1A_Thr178
ID Q9UBK2
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
AMPKPPARGC1AThr178NHNHRIRtNPAIVKTphosphorylation
up-regulates activity		20640476SIGNOR-209936
PRKAA1PPARGC1AThr178NHNHRIRtNPAIVKTphosphorylation
up-regulates activity		17609368SIGNOR-156780
AMPKPPARGC1AThr178NHNHRIRtNPAIVKTphosphorylation
up-regulates		17609368SIGNOR-216651
AMPKPPARGC1AThr178NHNHRIRtNPAIVKTphosphorylation
up-regulates activity		17609368SIGNOR-228642
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
AMPKphosphorylation
up-regulates
→
PPARGC1A
PThr178		phosphorylation
up-regulates
→		PPARGC1A20640476SIGNOR-209936
PRKAA1phosphorylation
up-regulates
→
PPARGC1A
PThr178		phosphorylation
up-regulates
→		PPARGC1A17609368SIGNOR-156780
AMPKphosphorylation
up-regulates
→
PPARGC1A
PThr178		phosphorylation
up-regulates
→		PPARGC1A17609368SIGNOR-216651
AMPKphosphorylation
up-regulates
→
PPARGC1A
PThr178		phosphorylation
up-regulates
→		PPARGC1A17609368SIGNOR-228642
Regulator Mechanism/Effect Target SIGNOR-ID
AMPKphosphorylation
→
up-regulates activity 		PPARGC1ASIGNOR-209936
PRKAA1phosphorylation
→
up-regulates activity 		PPARGC1ASIGNOR-156780
AMPKphosphorylation
→
up-regulates 		PPARGC1ASIGNOR-216651
AMPKphosphorylation
→
up-regulates activity 		PPARGC1ASIGNOR-228642