| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCE | RPS6KB2 | Ser473 | PPSGTKKsKRGRGRP | phosphorylation unknown | 12529391 | SIGNOR-97291 |
| PRKCD | RPS6KB2 | Ser473 | PPSGTKKsKRGRGRP | phosphorylation unknown | 12529391 | SIGNOR-97287 |
| PRKCB | RPS6KB2 | Ser473 | PPSGTKKsKRGRGRP | phosphorylation unknown | 12529391 | SIGNOR-97283 |
| PRKCG | RPS6KB2 | Ser473 | PPSGTKKsKRGRGRP | phosphorylation unknown | 12529391 | SIGNOR-97295 |
| PRKCA | RPS6KB2 | Ser473 | PPSGTKKsKRGRGRP | phosphorylation unknown | 12529391 | SIGNOR-97279 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCE | phosphorylation up-regulates → | RPS6KB2 PSer473 | phosphorylation down-regulates ⊣ | RPS6KB2 | 12529391 | SIGNOR-97291 |
| PRKCD | phosphorylation up-regulates → | RPS6KB2 PSer473 | phosphorylation down-regulates ⊣ | RPS6KB2 | 12529391 | SIGNOR-97287 |
| PRKCB | phosphorylation up-regulates → | RPS6KB2 PSer473 | phosphorylation down-regulates ⊣ | RPS6KB2 | 12529391 | SIGNOR-97283 |
| PRKCG | phosphorylation up-regulates → | RPS6KB2 PSer473 | phosphorylation down-regulates ⊣ | RPS6KB2 | 12529391 | SIGNOR-97295 |
| PRKCA | phosphorylation up-regulates → | RPS6KB2 PSer473 | phosphorylation down-regulates ⊣ | RPS6KB2 | 12529391 | SIGNOR-97279 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKCE | phosphorylation → unknown | RPS6KB2 | SIGNOR-97291 |
| PRKCD | phosphorylation → unknown | RPS6KB2 | SIGNOR-97287 |
| PRKCB | phosphorylation → unknown | RPS6KB2 | SIGNOR-97283 |
| PRKCG | phosphorylation → unknown | RPS6KB2 | SIGNOR-97295 |
| PRKCA | phosphorylation → unknown | RPS6KB2 | SIGNOR-97279 |
