| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK3 | GABBR1 | Thr873 | WQSEAQDtMKTGSST | phosphorylation down-regulates quantity by destabilization | 37686242 | SIGNOR-277855 |
| MAPK1 | GABBR1 | Thr873 | WQSEAQDtMKTGSST | phosphorylation down-regulates quantity by destabilization | 37686242 | SIGNOR-277857 |
| CAMK2B | GABBR1 | Thr873 | WQSEAQDtMKTGSST | phosphorylation down-regulates quantity by destabilization | 37686242 | SIGNOR-277850 |
| ERK1/2 | GABBR1 | Thr873 | WQSEAQDtMKTGSST | phosphorylation down-regulates quantity by destabilization | 37686242 | SIGNOR-277852 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK3 | phosphorylation up-regulates → | GABBR1 PThr873 | phosphorylation down-regulates ⊣ | GABBR1 | 37686242 | SIGNOR-277855 |
| MAPK1 | phosphorylation up-regulates → | GABBR1 PThr873 | phosphorylation down-regulates ⊣ | GABBR1 | 37686242 | SIGNOR-277857 |
| CAMK2B | phosphorylation up-regulates → | GABBR1 PThr873 | phosphorylation down-regulates ⊣ | GABBR1 | 37686242 | SIGNOR-277850 |
| ERK1/2 | phosphorylation up-regulates → | GABBR1 PThr873 | phosphorylation down-regulates ⊣ | GABBR1 | 37686242 | SIGNOR-277852 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPK3 | phosphorylation![]() down-regulates quantity by destabilization | GABBR1 | SIGNOR-277855 |
| MAPK1 | phosphorylation![]() down-regulates quantity by destabilization | GABBR1 | SIGNOR-277857 |
| CAMK2B | phosphorylation![]() down-regulates quantity by destabilization | GABBR1 | SIGNOR-277850 |
| ERK1/2 | phosphorylation![]() down-regulates quantity by destabilization | GABBR1 | SIGNOR-277852 |