| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ATR | DBF4 | Ser502 | FSTDNSGsQPKQKSD | phosphorylation down-regulates | 22123827 | SIGNOR-177805 |
| ATM | DBF4 | Ser502 | FSTDNSGsQPKQKSD | phosphorylation down-regulates | 22123827 | SIGNOR-177793 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ATR | phosphorylation up-regulates → | DBF4 PSer502 | phosphorylation down-regulates ⊣ | DBF4 | 22123827 | SIGNOR-177805 |
| ATM | phosphorylation up-regulates → | DBF4 PSer502 | phosphorylation down-regulates ⊣ | DBF4 | 22123827 | SIGNOR-177793 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| ATR | phosphorylation![]() down-regulates | DBF4 | SIGNOR-177805 |
| ATM | phosphorylation![]() down-regulates | DBF4 | SIGNOR-177793 |