Entity Details

Name ATM_Thr449
ID Q9UBU7
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
ATRDBF4Thr449DDIRQNFtQLPLHKNphosphorylation
down-regulates		22123827SIGNOR-177813
ATMDBF4Thr449DDIRQNFtQLPLHKNphosphorylation
down-regulates		22123827SIGNOR-177801
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
ATRphosphorylation
up-regulates
→
DBF4
PThr449		phosphorylation
down-regulates
⊣		DBF422123827SIGNOR-177813
ATMphosphorylation
up-regulates
→
DBF4
PThr449		phosphorylation
down-regulates
⊣		DBF422123827SIGNOR-177801
Regulator Mechanism/Effect Target SIGNOR-ID
ATRphosphorylation
img/direct_inhibition.png
down-regulates 		DBF4SIGNOR-177813
ATMphosphorylation
img/direct_inhibition.png
down-regulates 		DBF4SIGNOR-177801