| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PLK1 | ZMYM2 | Ser303 | QKQPGVDsLSPVASL | phosphorylation down-regulates quantity by destabilization | 25855382 | SIGNOR-275559 |
| PLK1 | ZMYM2 | Ser309 | DSLSPVAsLPKQIFQ | phosphorylation down-regulates quantity by destabilization | 25855382 | SIGNOR-275560 |
| PLK1 | ZMYM2 | – | phosphorylation down-regulates | 25855382 | SIGNOR-278491 | |
| PLK1 | ZMYM2 | Ser305 | QPGVDSLsPVASLPK | phosphorylation down-regulates quantity by destabilization | 25855382 | SIGNOR-275558 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PLK1 | phosphorylation up-regulates → | ZMYM2 PSer303 | phosphorylation down-regulates ⊣ | ZMYM2 | 25855382 | SIGNOR-275559 |
| PLK1 | phosphorylation up-regulates → | ZMYM2 PSer309 | phosphorylation down-regulates ⊣ | ZMYM2 | 25855382 | SIGNOR-275560 |
| PLK1 | phosphorylation up-regulates → | ZMYM2 PSer305 | phosphorylation down-regulates ⊣ | ZMYM2 | 25855382 | SIGNOR-275558 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PLK1 | phosphorylation![]() down-regulates quantity by destabilization | ZMYM2 | SIGNOR-275559 |
| PLK1 | phosphorylation![]() down-regulates quantity by destabilization | ZMYM2 | SIGNOR-275560 |
| PLK1 | phosphorylation![]() down-regulates | ZMYM2 | SIGNOR-278491 |
| PLK1 | phosphorylation![]() down-regulates quantity by destabilization | ZMYM2 | SIGNOR-275558 |