Entity Details

Name STAP2
ID Q9UGK3
Role substrate
Enzymatic Domains
PH 18-130
SH2 133-248
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PTK6STAP2–phosphorylation
up-regulates		10980601SIGNOR-81489
SRCSTAP2Tyr22GVLPSHYyESFLEKKphosphorylation
up-regulates activity		12540842SIGNOR-247333
JAK2STAP2Tyr250
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PFLLDEDyEKVLGYVphosphorylation
up-regulates activity		12540842SIGNOR-249371
PTK6STAP2Tyr250
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PFLLDEDyEKVLGYVphosphorylation
up-regulates activity		19393627SIGNOR-247067
JAK2STAP2Tyr310LPNQEENyVTPIGDGphosphorylation
up-regulates activity		12540842SIGNOR-249372
SRCSTAP2Tyr322GDGPAVDyENQDVASphosphorylation
up-regulates activity		12540842SIGNOR-247337
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
SRCphosphorylation
up-regulates
→
STAP2
PTyr22		phosphorylation
up-regulates
→		STAP212540842SIGNOR-247333
JAK2phosphorylation
up-regulates
→
STAP2
PTyr250		phosphorylation
up-regulates
→		STAP212540842SIGNOR-249371
PTK6phosphorylation
up-regulates
→
STAP2
PTyr250		phosphorylation
up-regulates
→		STAP219393627SIGNOR-247067
JAK2phosphorylation
up-regulates
→
STAP2
PTyr310		phosphorylation
up-regulates
→		STAP212540842SIGNOR-249372
SRCphosphorylation
up-regulates
→
STAP2
PTyr322		phosphorylation
up-regulates
→		STAP212540842SIGNOR-247337
Regulator Mechanism/Effect Target SIGNOR-ID
PTK6phosphorylation
→
up-regulates 		STAP2SIGNOR-81489
SRCphosphorylation
→
up-regulates activity 		STAP2SIGNOR-247333
JAK2phosphorylation
→
up-regulates activity 		STAP2SIGNOR-249371
PTK6phosphorylation
→
up-regulates activity 		STAP2SIGNOR-247067
JAK2phosphorylation
→
up-regulates activity 		STAP2SIGNOR-249372
SRCphosphorylation
→
up-regulates activity 		STAP2SIGNOR-247337