Entity Details

Name POLL
ID Q9UGP5
Role substrate
Enzymatic Domains
BRCT 36-132
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PRKDCPOLLThr204EASDGEEtQVSAADLphosphorylation
up-regulates activity		28109743SIGNOR-273835
CyclinA2/CDK2POLLThr553GPGRVLPtPTEKDVFphosphorylation
up-regulates quantity by stabilization		18688254SIGNOR-273595
ATMPOLLThr204EASDGEEtQVSAADLphosphorylation
up-regulates activity		28109743SIGNOR-273836
ATMPOLLThr204EASDGEEtQVSAADLphosphorylation
up-regulates activity		28109743SIGNOR-273510
CDK2POLL–phosphorylation
up-regulates activity		16174846SIGNOR-278919
CDK2POLLThr553GPGRVLPtPTEKDVFphosphorylation
up-regulates quantity by stabilization		18688254SIGNOR-276169
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PRKDCphosphorylation
up-regulates
→
POLL
PThr204		phosphorylation
up-regulates
→		POLL28109743SIGNOR-273835
CyclinA2/CDK2phosphorylation
up-regulates
→
POLL
PThr553		phosphorylation
up-regulates
→		POLL18688254SIGNOR-273595
ATMphosphorylation
up-regulates
→
POLL
PThr204		phosphorylation
up-regulates
→		POLL28109743SIGNOR-273836
ATMphosphorylation
up-regulates
→
POLL
PThr204		phosphorylation
up-regulates
→		POLL28109743SIGNOR-273510
CDK2phosphorylation
up-regulates
→
POLL
PThr553		phosphorylation
up-regulates
→		POLL18688254SIGNOR-276169
Regulator Mechanism/Effect Target SIGNOR-ID
PRKDCphosphorylation
→
up-regulates activity 		POLLSIGNOR-273835
CyclinA2/CDK2phosphorylation
→
up-regulates quantity by stabilization 		POLLSIGNOR-273595
ATMphosphorylation
→
up-regulates activity 		POLLSIGNOR-273836
ATMphosphorylation
→
up-regulates activity 		POLLSIGNOR-273510
CDK2phosphorylation
→
up-regulates activity 		POLLSIGNOR-278919
CDK2phosphorylation
→
up-regulates quantity by stabilization 		POLLSIGNOR-276169