Entity Details

Name LIMA1
ID Q9UHB6
Role substrate
Enzymatic Domains
LIM zinc-binding 388-448
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
MAPK1LIMA1Ser604
View in OncoXplorer
FQSTSVKsPKTVSPPphosphorylation
down-regulates quantity by destabilization		23188829SIGNOR-263055
ERK1/2LIMA1Ser604
View in OncoXplorer
FQSTSVKsPKTVSPPphosphorylation
down-regulates quantity by destabilization		23188829SIGNOR-263063
MAPK1LIMA1Ser362
View in OncoXplorer
PVHPKPLsPDSRASSphosphorylation
down-regulates quantity by destabilization		23188829SIGNOR-263054
ERK1/2LIMA1Ser362
View in OncoXplorer
PVHPKPLsPDSRASSphosphorylation
down-regulates quantity by destabilization		23188829SIGNOR-263062
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
MAPK1phosphorylation
up-regulates
→
LIMA1
PSer604		phosphorylation
down-regulates
⊣		LIMA123188829SIGNOR-263055
ERK1/2phosphorylation
up-regulates
→
LIMA1
PSer604		phosphorylation
down-regulates
⊣		LIMA123188829SIGNOR-263063
MAPK1phosphorylation
up-regulates
→
LIMA1
PSer362		phosphorylation
down-regulates
⊣		LIMA123188829SIGNOR-263054
ERK1/2phosphorylation
up-regulates
→
LIMA1
PSer362		phosphorylation
down-regulates
⊣		LIMA123188829SIGNOR-263062
Regulator Mechanism/Effect Target SIGNOR-ID
MAPK1phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		LIMA1SIGNOR-263055
ERK1/2phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		LIMA1SIGNOR-263063
MAPK1phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		LIMA1SIGNOR-263054
ERK1/2phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		LIMA1SIGNOR-263062