| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK1 | LIMA1 | Ser604 | FQSTSVKsPKTVSPP | phosphorylation down-regulates quantity by destabilization | 23188829 | SIGNOR-263055 |
| ERK1/2 | LIMA1 | Ser604 | FQSTSVKsPKTVSPP | phosphorylation down-regulates quantity by destabilization | 23188829 | SIGNOR-263063 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK1 | phosphorylation up-regulates → | LIMA1 PSer604 | phosphorylation down-regulates ⊣ | LIMA1 | 23188829 | SIGNOR-263055 |
| ERK1/2 | phosphorylation up-regulates → | LIMA1 PSer604 | phosphorylation down-regulates ⊣ | LIMA1 | 23188829 | SIGNOR-263063 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPK1 | phosphorylation![]() down-regulates quantity by destabilization | LIMA1 | SIGNOR-263055 |
| ERK1/2 | phosphorylation![]() down-regulates quantity by destabilization | LIMA1 | SIGNOR-263063 |