| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| DYRK2 | TBK1 | Ser527 | QDIDSRLsPGGSLAD | phosphorylation down-regulates quantity by destabilization | 26407194 | SIGNOR-276939 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| DYRK2 | phosphorylation up-regulates → | TBK1 PSer527 | phosphorylation down-regulates ⊣ | TBK1 | 26407194 | SIGNOR-276939 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| DYRK2 | phosphorylation![]() down-regulates quantity by destabilization | TBK1 | SIGNOR-276939 |