Entity Details

Name HCK_Tyr394
ID Q9UHD2
Role residue
View in

Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
LCKTBK1Tyr394LNTIGLIyEKISLPKphosphorylation
down-regulates activity		28618271SIGNOR-276723
FGRTBK1Tyr394LNTIGLIyEKISLPKphosphorylation
down-regulates activity		28618271SIGNOR-276722
HCKTBK1Tyr394LNTIGLIyEKISLPKphosphorylation
down-regulates activity		28618271SIGNOR-276727
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
LCKphosphorylation
up-regulates
→
TBK1
PTyr394		phosphorylation
down-regulates
⊣		TBK128618271SIGNOR-276723
FGRphosphorylation
up-regulates
→
TBK1
PTyr394		phosphorylation
down-regulates
⊣		TBK128618271SIGNOR-276722
HCKphosphorylation
up-regulates
→
TBK1
PTyr394		phosphorylation
down-regulates
⊣		TBK128618271SIGNOR-276727
Regulator Mechanism/Effect Target SIGNOR-ID
LCKphosphorylation
→
down-regulates activity 		TBK1SIGNOR-276723
FGRphosphorylation
→
down-regulates activity 		TBK1SIGNOR-276722
HCKphosphorylation
→
down-regulates activity 		TBK1SIGNOR-276727