Entity Details

Name WNK1_Thr991
ID Q9UHW9
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
WNK1SLC12A6Thr991SAYTYERtLMMEQRSphosphorylation
down-regulates		19665974SIGNOR-187564
WNK3SLC12A6Thr991SAYTYERtLMMEQRSphosphorylation
down-regulates activity		24043619SIGNOR-260912
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
WNK1phosphorylation
up-regulates
→
SLC12A6
PThr991		phosphorylation
down-regulates
⊣		SLC12A619665974SIGNOR-187564
WNK3phosphorylation
up-regulates
→
SLC12A6
PThr991		phosphorylation
down-regulates
⊣		SLC12A624043619SIGNOR-260912
Regulator Mechanism/Effect Target SIGNOR-ID
WNK1phosphorylation
img/direct_inhibition.png
down-regulates 		SLC12A6SIGNOR-187564
WNK3phosphorylation
→
down-regulates activity 		SLC12A6SIGNOR-260912