Entity Details

Name ERRFI1
ID Q9UJM3
Role substrate
Enzymatic Domains
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
SRCERRFI1–phosphorylation
down-regulates activity		26280531SIGNOR-279116
EGFRERRFI1Tyr394
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KKVSSTHyYLLPERPphosphorylation
up-regulates activity		26280531SIGNOR-252091
CHEK1ERRFI1Ser251
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RRLRRSHsGPAGSFNphosphorylation
down-regulates activity		22505024SIGNOR-276411
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
EGFRphosphorylation
up-regulates
→
ERRFI1
PTyr394		phosphorylation
up-regulates
→		ERRFI126280531SIGNOR-252091
CHEK1phosphorylation
up-regulates
→
ERRFI1
PSer251		phosphorylation
down-regulates
⊣		ERRFI122505024SIGNOR-276411
Regulator Mechanism/Effect Target SIGNOR-ID
SRCphosphorylation
→
down-regulates activity 		ERRFI1SIGNOR-279116
EGFRphosphorylation
→
up-regulates activity 		ERRFI1SIGNOR-252091
CHEK1phosphorylation
→
down-regulates activity 		ERRFI1SIGNOR-276411