| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CHEK1 | TLK1 | Ser743 | PHMRRSNsSGNLHMA | phosphorylation down-regulates | 12660173 | SIGNOR-99653 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CHEK1 | phosphorylation up-regulates → | TLK1 PSer743 | phosphorylation down-regulates ⊣ | TLK1 | 12660173 | SIGNOR-99653 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CHEK1 | phosphorylation![]() down-regulates | TLK1 | SIGNOR-99653 |