Entity Details

Name TPX2_Thr72
ID Q9ULW0
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CDK1TPX2Thr72
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NLQQAIVtPLKPVDNphosphorylation
down-regulates activity		25688093SIGNOR-265096
CDK2TPX2Thr72
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NLQQAIVtPLKPVDNphosphorylation
down-regulates activity		25688093SIGNOR-265099
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CDK1phosphorylation
up-regulates
→
TPX2
PThr72		phosphorylation
down-regulates
⊣		TPX225688093SIGNOR-265096
CDK2phosphorylation
up-regulates
→
TPX2
PThr72		phosphorylation
down-regulates
⊣		TPX225688093SIGNOR-265099
Regulator Mechanism/Effect Target SIGNOR-ID
CDK1phosphorylation
→
down-regulates activity 		TPX2SIGNOR-265096
CDK2phosphorylation
→
down-regulates activity 		TPX2SIGNOR-265099