Entity Details

Name FZR1
ID Q9UM11
Role substrate
Enzymatic Domains
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CDK2FZR1Ser163KSQKLLRsPRKPTRKphosphorylation
down-regulates activity		12560341SIGNOR-250733
CDK2FZR1Ser151DVSPYSLsPVSNKSQphosphorylation
down-regulates activity		12560341SIGNOR-250732
PIM1FZR1–phosphorylation
down-regulates activity		20663873SIGNOR-259820
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CDK2phosphorylation
up-regulates
→
FZR1
PSer163		phosphorylation
down-regulates
⊣		FZR112560341SIGNOR-250733
CDK2phosphorylation
up-regulates
→
FZR1
PSer151		phosphorylation
down-regulates
⊣		FZR112560341SIGNOR-250732
Regulator Mechanism/Effect Target SIGNOR-ID
CDK2phosphorylation
→
down-regulates activity 		FZR1SIGNOR-250733
CDK2phosphorylation
→
down-regulates activity 		FZR1SIGNOR-250732
PIM1phosphorylation
→
down-regulates activity 		FZR1SIGNOR-259820