Entity Details

Name DAPP1
ID Q9UN19
Role substrate
Enzymatic Domains
SH2 35-129
PROSITE-ProRule
PH 164-259
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
BTKDAPP1Tyr139
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KVEEPSIyESVRVHTphosphorylation
up-regulates activity		10880360SIGNOR-249313
BTKDAPP1Tyr139
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KVEEPSIyESVRVHTphosphorylation
up-regulates activity		11524430SIGNOR-250602
LYNDAPP1Tyr139
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KVEEPSIyESVRVHTphosphorylation
up-regulates activity		10880360SIGNOR-249378
LCKDAPP1Tyr139
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KVEEPSIyESVRVHTphosphorylation
up-regulates activity		10880360SIGNOR-249373
SRCDAPP1Tyr139
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KVEEPSIyESVRVHTphosphorylation
up-regulates activity		10880360SIGNOR-247119
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
BTKphosphorylation
up-regulates
→
DAPP1
PTyr139		phosphorylation
up-regulates
→		DAPP110880360SIGNOR-249313
BTKphosphorylation
up-regulates
→
DAPP1
PTyr139		phosphorylation
up-regulates
→		DAPP111524430SIGNOR-250602
LYNphosphorylation
up-regulates
→
DAPP1
PTyr139		phosphorylation
up-regulates
→		DAPP110880360SIGNOR-249378
LCKphosphorylation
up-regulates
→
DAPP1
PTyr139		phosphorylation
up-regulates
→		DAPP110880360SIGNOR-249373
SRCphosphorylation
up-regulates
→
DAPP1
PTyr139		phosphorylation
up-regulates
→		DAPP110880360SIGNOR-247119
Regulator Mechanism/Effect Target SIGNOR-ID
BTKphosphorylation
→
up-regulates activity 		DAPP1SIGNOR-249313
BTKphosphorylation
→
up-regulates activity 		DAPP1SIGNOR-250602
LYNphosphorylation
→
up-regulates activity 		DAPP1SIGNOR-249378
LCKphosphorylation
→
up-regulates activity 		DAPP1SIGNOR-249373
SRCphosphorylation
→
up-regulates activity 		DAPP1SIGNOR-247119