Entity Details

Name FAF1
ID Q9UNN5
Role substrate
Enzymatic Domains
UBA 1-57
PubMed
UBX 569-646
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CSNK2A1FAF1Ser291DVHMVSDsDGDDFEDphosphorylation
down-regulates activity		12832043SIGNOR-250864
IKBKEFAF1Ser556EREAIRLsLEQALPPphosphorylation
down-regulates quantity by destabilization		30472208SIGNOR-277618
AURKAFAF1Ser291DVHMVSDsDGDDFEDphosphorylation
down-regulates activity		18790738SIGNOR-180891
CSNK2A1FAF1Ser289ITDVHMVsDSDGDDFphosphorylation
down-regulates activity		12832043SIGNOR-250863
AURKAFAF1Ser289ITDVHMVsDSDGDDFphosphorylation
down-regulates activity		18790738SIGNOR-180887
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CSNK2A1phosphorylation
up-regulates
→
FAF1
PSer291		phosphorylation
down-regulates
⊣		FAF112832043SIGNOR-250864
IKBKEphosphorylation
up-regulates
→
FAF1
PSer556		phosphorylation
down-regulates
⊣		FAF130472208SIGNOR-277618
AURKAphosphorylation
up-regulates
→
FAF1
PSer291		phosphorylation
down-regulates
⊣		FAF118790738SIGNOR-180891
CSNK2A1phosphorylation
up-regulates
→
FAF1
PSer289		phosphorylation
down-regulates
⊣		FAF112832043SIGNOR-250863
AURKAphosphorylation
up-regulates
→
FAF1
PSer289		phosphorylation
down-regulates
⊣		FAF118790738SIGNOR-180887
Regulator Mechanism/Effect Target SIGNOR-ID
CSNK2A1phosphorylation
→
down-regulates activity 		FAF1SIGNOR-250864
IKBKEphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		FAF1SIGNOR-277618
AURKAphosphorylation
→
down-regulates activity 		FAF1SIGNOR-180891
CSNK2A1phosphorylation
→
down-regulates activity 		FAF1SIGNOR-250863
AURKAphosphorylation
→
down-regulates activity 		FAF1SIGNOR-180887