Entity Details

Name CILK1
ID Q9UPZ9
Role kinase
Enzymatic Domains
Protein kinase 4-284
PROSITE-ProRule|
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CILK1RPTORThr908LPSGRPGtTGPAGAQphosphorylation
up-regulates		22356909SIGNOR-196198
CILK1CILK1Tyr159SKPPYTDyVSTRWYRphosphorylation
up-regulates		15988018SIGNOR-138424
CILK1mTORC1–phosphorylation
up-regulates		22356909SIGNOR-217562
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CILK1phosphorylation
up-regulates
→
RPTOR
PThr908		phosphorylation
up-regulates
→		RPTOR22356909SIGNOR-196198
CILK1phosphorylation
up-regulates
→
CILK1
PTyr159		phosphorylation
up-regulates
→		CILK115988018SIGNOR-138424
Regulator Mechanism/Effect Target SIGNOR-ID
CILK1phosphorylation
→
up-regulates 		RPTORSIGNOR-196198
CILK1phosphorylation
→
up-regulates 		CILK1SIGNOR-138424
CILK1phosphorylation
→
up-regulates 		mTORC1SIGNOR-217562