| Name | AURKC |
| ID | Q9UQB9 |
| Role | kinase |
| Enzymatic Domains |
Protein kinase 43-293 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AURKC | TACC1 | Ser228 | ELVPSRRsKLRKPKP | phosphorylation up-regulates activity | 21531210 | SIGNOR-262663 |
| AURKC | NFKBIA | Ser32 | LLDDRHDsGLDSMKD | phosphorylation up-regulates activity | 29050234 | SIGNOR-278470 |
| AURKC | H3C1 | Ser11 | TKQTARKsTGGKAPR | phosphorylation up-regulates activity | 12588998 | SIGNOR-98361 |
| AURKC | H3C1 | Ser11 | TKQTARKsTGGKAPR | phosphorylation up-regulates activity | 14583461 | SIGNOR-118898 |
| AURKC | Histone H3 | – | phosphorylation up-regulates | 12588998 | SIGNOR-265357 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AURKC | phosphorylation up-regulates → | TACC1 PSer228 | phosphorylation up-regulates → | TACC1 | 21531210 | SIGNOR-262663 |
| AURKC | phosphorylation up-regulates → | NFKBIA PSer32 | phosphorylation up-regulates → | NFKBIA | 29050234 | SIGNOR-278470 |
| AURKC | phosphorylation up-regulates → | H3C1 PSer11 | phosphorylation up-regulates → | H3C1 | 12588998 | SIGNOR-98361 |
| AURKC | phosphorylation up-regulates → | H3C1 PSer11 | phosphorylation up-regulates → | H3C1 | 14583461 | SIGNOR-118898 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| AURKC | phosphorylation → up-regulates activity | TACC1 | SIGNOR-262663 |
| AURKC | phosphorylation → up-regulates activity | NFKBIA | SIGNOR-278470 |
| AURKC | phosphorylation → up-regulates activity | H3C1 | SIGNOR-98361 |
| AURKC | phosphorylation → up-regulates activity | H3C1 | SIGNOR-118898 |
| AURKC | phosphorylation → up-regulates | Histone H3 | SIGNOR-265357 |