| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AKT | GAB2 | Ser159 | LLRERKSsAPSHSSQ | phosphorylation down-regulates | 11782427 | SIGNOR-113669 |
| AKT1 | GAB2 | Ser159 | LLRERKSsAPSHSSQ | phosphorylation down-regulates | 11782427 | SIGNOR-252468 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AKT | phosphorylation up-regulates → | GAB2 PSer159 | phosphorylation down-regulates ⊣ | GAB2 | 11782427 | SIGNOR-113669 |
| AKT1 | phosphorylation up-regulates → | GAB2 PSer159 | phosphorylation down-regulates ⊣ | GAB2 | 11782427 | SIGNOR-252468 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| AKT | phosphorylation![]() down-regulates | GAB2 | SIGNOR-113669 |
| AKT1 | phosphorylation![]() down-regulates | GAB2 | SIGNOR-252468 |