Entity Details

Name SCN8A
ID Q9UQD0
Role substrate
Enzymatic Domains
IQ 1895-1924
PROSITE-ProRule|
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CAMK2GSCN8ASer561PFLSRHNsKSSIFSFphosphorylation
up-regulates activity		32611770SIGNOR-275793
GSK3BSCN8AThr1938HREKKEStPSTASLPphosphorylation
up-regulates activity		29642012SIGNOR-275763
CAMK2BSCN8AThr642RSVKRNStVDCNGVVphosphorylation
up-regulates activity		32611770SIGNOR-275789
CAMK2DSCN8ASer561PFLSRHNsKSSIFSFphosphorylation
up-regulates activity		32611770SIGNOR-275790
CAMK2DSCN8ASer641RRSVKRNsTVDCNGVphosphorylation
up-regulates activity		32611770SIGNOR-275791
CAMK2DSCN8AThr642RSVKRNStVDCNGVVphosphorylation
up-regulates activity		32611770SIGNOR-275792
CAMK2BSCN8ASer561PFLSRHNsKSSIFSFphosphorylation
up-regulates activity		32611770SIGNOR-275787
CAMK2GSCN8ASer641RRSVKRNsTVDCNGVphosphorylation
up-regulates activity		32611770SIGNOR-275794
CAMK2GSCN8AThr642RSVKRNStVDCNGVVphosphorylation
up-regulates activity		32611770SIGNOR-275795
CAMK2BSCN8ASer641RRSVKRNsTVDCNGVphosphorylation
up-regulates activity		32611770SIGNOR-275788
CAMK2ASCN8ASer641RRSVKRNsTVDCNGVphosphorylation
up-regulates activity		32611770SIGNOR-275785
CAMK2ASCN8ASer561PFLSRHNsKSSIFSFphosphorylation
up-regulates activity		32611770SIGNOR-275784
CAMK2ASCN8AThr642RSVKRNStVDCNGVVphosphorylation
up-regulates activity		32611770SIGNOR-275786
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CAMK2Gphosphorylation
up-regulates
→
SCN8A
PSer561		phosphorylation
up-regulates
→		SCN8A32611770SIGNOR-275793
GSK3Bphosphorylation
up-regulates
→
SCN8A
PThr1938		phosphorylation
up-regulates
→		SCN8A29642012SIGNOR-275763
CAMK2Bphosphorylation
up-regulates
→
SCN8A
PThr642		phosphorylation
up-regulates
→		SCN8A32611770SIGNOR-275789
CAMK2Dphosphorylation
up-regulates
→
SCN8A
PSer561		phosphorylation
up-regulates
→		SCN8A32611770SIGNOR-275790
CAMK2Dphosphorylation
up-regulates
→
SCN8A
PSer641		phosphorylation
up-regulates
→		SCN8A32611770SIGNOR-275791
CAMK2Dphosphorylation
up-regulates
→
SCN8A
PThr642		phosphorylation
up-regulates
→		SCN8A32611770SIGNOR-275792
CAMK2Bphosphorylation
up-regulates
→
SCN8A
PSer561		phosphorylation
up-regulates
→		SCN8A32611770SIGNOR-275787
CAMK2Gphosphorylation
up-regulates
→
SCN8A
PSer641		phosphorylation
up-regulates
→		SCN8A32611770SIGNOR-275794
CAMK2Gphosphorylation
up-regulates
→
SCN8A
PThr642		phosphorylation
up-regulates
→		SCN8A32611770SIGNOR-275795
CAMK2Bphosphorylation
up-regulates
→
SCN8A
PSer641		phosphorylation
up-regulates
→		SCN8A32611770SIGNOR-275788
CAMK2Aphosphorylation
up-regulates
→
SCN8A
PSer641		phosphorylation
up-regulates
→		SCN8A32611770SIGNOR-275785
CAMK2Aphosphorylation
up-regulates
→
SCN8A
PSer561		phosphorylation
up-regulates
→		SCN8A32611770SIGNOR-275784
CAMK2Aphosphorylation
up-regulates
→
SCN8A
PThr642		phosphorylation
up-regulates
→		SCN8A32611770SIGNOR-275786
Regulator Mechanism/Effect Target SIGNOR-ID
CAMK2Gphosphorylation
→
up-regulates activity 		SCN8ASIGNOR-275793
GSK3Bphosphorylation
→
up-regulates activity 		SCN8ASIGNOR-275763
CAMK2Bphosphorylation
→
up-regulates activity 		SCN8ASIGNOR-275789
CAMK2Dphosphorylation
→
up-regulates activity 		SCN8ASIGNOR-275790
CAMK2Dphosphorylation
→
up-regulates activity 		SCN8ASIGNOR-275791
CAMK2Dphosphorylation
→
up-regulates activity 		SCN8ASIGNOR-275792
CAMK2Bphosphorylation
→
up-regulates activity 		SCN8ASIGNOR-275787
CAMK2Gphosphorylation
→
up-regulates activity 		SCN8ASIGNOR-275794
CAMK2Gphosphorylation
→
up-regulates activity 		SCN8ASIGNOR-275795
CAMK2Bphosphorylation
→
up-regulates activity 		SCN8ASIGNOR-275788
CAMK2Aphosphorylation
→
up-regulates activity 		SCN8ASIGNOR-275785
CAMK2Aphosphorylation
→
up-regulates activity 		SCN8ASIGNOR-275784
CAMK2Aphosphorylation
→
up-regulates activity 		SCN8ASIGNOR-275786