Entity Details

Name PRKACA_Ser279
ID Q9UQL6
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
DYRK1BHDAC5Ser279KVAERRSsPLLRRKDphosphorylation
down-regulates activity		15546868SIGNOR-235809
PRKACAHDAC5Ser279KVAERRSsPLLRRKDphosphorylation
up-regulates activity		22865920SIGNOR-198658
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
DYRK1Bphosphorylation
up-regulates
→
HDAC5
PSer279		phosphorylation
down-regulates
⊣		HDAC515546868SIGNOR-235809
PRKACAphosphorylation
up-regulates
→
HDAC5
PSer279		phosphorylation
up-regulates
→		HDAC522865920SIGNOR-198658
Regulator Mechanism/Effect Target SIGNOR-ID
DYRK1Bphosphorylation
→
down-regulates activity 		HDAC5SIGNOR-235809
PRKACAphosphorylation
→
up-regulates activity 		HDAC5SIGNOR-198658