Entity Details

Name CAMK2A
ID Q9UQM7
Role kinase
Enzymatic Domains
Protein kinase 13-271
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CAMK2ASCN8AThr642RSVKRNStVDCNGVVphosphorylation
up-regulates activity
32611770SIGNOR-275786
CAMK2ADAGLASer808RSIRGSPsLHAVLERphosphorylation
down-regulates activity
23502535SIGNOR-275540
CAMK2ACACNA1HSer2137RDLRRLYsVDAQGFLphosphorylation
down-regulates activity
38001892SIGNOR-277871
CAMK2ACAMK2ASer314MLATRNFsGGKSGGNphosphorylation
down-regulates
1324926SIGNOR-17308
CAMK2ASTMN1Ser16KELEKRAsGQAFELIphosphorylation
down-regulates
16982419SIGNOR-149640
CAMK2ASTMN1Ser16KELEKRAsGQAFELIphosphorylation
down-regulates
9686569SIGNOR-59354
CAMK2AGFAPSer38LGPGTRLsLARMPPPphosphorylation
down-regulates activity
7822264SIGNOR-250628
CAMK2AMAPTSer552VVRTPPKsPSSAKSRphosphorylation
down-regulates activity
10090741SIGNOR-249316
CAMK2AETS1Ser282NSLQRVPsYDSFDSEphosphorylation
down-regulates
12475968SIGNOR-96338
CAMK2AMAPTThr548KKVAVVRtPPKSPSSphosphorylation
down-regulates activity
10090741SIGNOR-249315
CAMK2AHOMER3Ser120ARLAREKsQDGGELTphosphorylation
down-regulates activity
18480293SIGNOR-262684
CAMK2APTTG1Ser89KQKQPSFsAKKMTEKphosphorylation
down-regulates quantity by destabilization
24781523SIGNOR-276383
CAMK2ACACNA1SSer1575PEICRTVsGDLAAEEphosphorylation
up-regulates activity
20937870SIGNOR-263113
CAMK2ARCHY1Ser155CLEDIHTsRVVAHVLphosphorylation
down-regulates
17568776SIGNOR-156064
CAMK2ASYNGAP1Ser780MARGLNSsMDMARLPphosphorylation
up-regulates activity
14970204SIGNOR-262690
CAMK2ACYLDSer772LFKKIFPsLELNITDphosphorylation
up-regulates activity
24614225SIGNOR-266433
CAMK2APDCSer73ERVSRKMsIQEYELIphosphorylation
unknown
11331285SIGNOR-250637
CAMK2APTTG1Ser31LKLGSGPsIKALDGRphosphorylation
down-regulates quantity by destabilization
24781523SIGNOR-276382
CAMK2ARIMS1Ser242PSAPPDRsKGAEPSQphosphorylation
up-regulates
12871946SIGNOR-103886
CAMK2ANOX5Ser547TMRKSQRsSKGSEILphosphorylation
unknown
21642394SIGNOR-276332
CAMK2AATP2A2Ser38KLKERWGsNELPAEEphosphorylation
up-regulates activity
7929371SIGNOR-250616
CAMK2ARIMS1Ser288NGKGALKsERKRVPKphosphorylation
up-regulates
12871946SIGNOR-103890
CAMK2ASCN5ASer571PWPLRRTsAQGQPSPphosphorylation
up-regulates activity
33410863SIGNOR-275771
CAMK2ASRFSer103RGLKRSLsEMEIGMVphosphorylation
up-regulates activity
10753652SIGNOR-250638
CAMK2AETS2Ser313QRVPSFEsFEDDCSQphosphorylation
down-regulates
19182667SIGNOR-183604
CAMK2AALOX5Ser272CSLERQLsLEQEVQQphosphorylation
up-regulates activity
18978352SIGNOR-264408
CAMK2AITPKAThr311EHAQRAVtKPRYMQWphosphorylation
up-regulates
9155020SIGNOR-48387
CAMK2AGFPT1Ser261CNLSRVDsTTCLFPVphosphorylation
up-regulates
17941647SIGNOR-158486
CAMK2ACD44Ser706LNGEASKsQEMVHLVphosphorylation
up-regulates
9580567SIGNOR-57376
CAMK2AITGB1BP1Thr38GGLSRSStVASLDTDphosphorylation
up-regulates activity
9813144SIGNOR-250632
CAMK2ANOX5Ser548MRKSQRSsKGSEILLphosphorylation
unknown
21642394SIGNOR-276333
CAMK2AANKS1Bphosphorylation
down-regulates activity
27477489SIGNOR-264231
CAMK2ACYLDSer772LFKKIFPsLELNITDphosphorylation
up-regulates activity
24614225SIGNOR-266441
CAMK2AMAPTSer579NVKSKIGsTENLKHQphosphorylation
down-regulates activity
10090741SIGNOR-249314
CAMK2ASYNGAP1Ser1073PPLQRGKsQQLTVSAphosphorylation
up-regulates activity
14970204SIGNOR-262687
CAMK2APEA15Ser116KDIIRQPsEEEIIKLphosphorylation
up-regulates
15916534SIGNOR-137614
CAMK2ASCN5ASer516LSLTRGLsRTSMKPRphosphorylation
up-regulates activity
33410863SIGNOR-275770
CAMK2ASYNGAP1Ser1138PSITKQHsQTPSTLNphosphorylation
up-regulates activity
14970204SIGNOR-262688
CAMK2AOPRM1Ser270SVRMLSGsKEKDRNLphosphorylation
down-regulates
10908300SIGNOR-79682
CAMK2AGRIA4Ser862IRNKARLsITGSVGEphosphorylation
up-regulates
12536214SIGNOR-97546
CAMK2ACREB1Ser142RKILNDLsSDAPGVPphosphorylation
down-regulates
11013247SIGNOR-82501
CAMK2AGLO1Thr107ELTHNWGtEDDETQSphosphorylation
up-regulates activity
32966793SIGNOR-273553
CAMK2ACEBPBSer325EQLSRELsTLRNLFKphosphorylation
up-regulates activity
1314426SIGNOR-250617
CAMK2ACAMK2AThr286 SCMHRQEtVDCLKKFphosphorylation
up-regulates
1849884SIGNOR-21797
CAMK2ATHSer19KGFRRAVsELDAKQAphosphorylation
up-regulates
1680128SIGNOR-20912
CAMK2AOPRM1Thr372STRIRQNtRDHPSTAphosphorylation
down-regulates
10908300SIGNOR-79686
CAMK2AMAPTphosphorylation
down-regulates
15621017SIGNOR-255490
CAMK2APKD2L1Thr591LKQGYNKtLLRLRLRphosphorylation
down-regulates activity
37193065SIGNOR-277812
CAMK2AHSF1Ser230PKYSRQFsLEHVHGSphosphorylation
up-regulates activity
11447121SIGNOR-250631
CAMK2AAMPAphosphorylation
up-regulates
12536214SIGNOR-270230
CAMK2ASYNGAP1Ser779FMARGLNsSMDMARLphosphorylation
up-regulates activity
14970204SIGNOR-262689
CAMK2ACALD1Ser656RAEFLNKsVQKSSGVphosphorylation
down-regulates
2170388SIGNOR-22635
CAMK2ACREB1Ser142RKILNDLsSDAPGVPphosphorylation
down-regulates
11970864SIGNOR-117344
CAMK2ACACNA1BSer2120ERRQPSSsSSEKQRFphosphorylation
down-regulates
16982421SIGNOR-149684
CAMK2ASLNThr5tRELFLNFphosphorylation
down-regulates activity
23455424SIGNOR-264778
CAMK2AEGFRSer1166QKGSHQIsLDNPDYQphosphorylation
down-regulates activity
10347170SIGNOR-250624
CAMK2AEGFRSer768DEAYVMAsVDNPHVCphosphorylation
down-regulates activity
10347170SIGNOR-250625
CAMK2AEGFRSer1081TGALTEDsIDDTFLPphosphorylation
down-regulates activity
10347170SIGNOR-250622
CAMK2ASMAD2Ser260TLSPVNHsLDLQPVTphosphorylation
down-regulates
11027280SIGNOR-82974
CAMK2AHRH1Thr140LRYLKYRtKTRASATphosphorylation
down-regulates
15107581SIGNOR-124348
CAMK2ASCN5AThr594LHGKKNStVDCNGVVphosphorylation
up-regulates activity
33410863SIGNOR-275772
CAMK2AOPRM1Ser268LKSVRMLsGSKEKDRphosphorylation
down-regulates
10908300SIGNOR-79678
CAMK2AETS1Ser251GKLGGQDsFESIESYphosphorylation
down-regulates
12475968SIGNOR-96330
CAMK2AEGFRSer1071SFLQRYSsDPTGALTphosphorylation
down-regulates activity
10347170SIGNOR-250621
CAMK2ADLGAP1Ser356KAMGDEDsGDSDTSPphosphorylation
down-regulates quantity by destabilization
23143515SIGNOR-276429
CAMK2AEGFRSer1070DSFLQRYsSDPTGALphosphorylation
down-regulates activity
10347170SIGNOR-250620
CAMK2ACALD1Ser643CFTPKGSsLKIEERAphosphorylation
down-regulates
2170388SIGNOR-22631
CAMK2ASMAD2Ser110SFSEQTRsLDGRLQVphosphorylation
down-regulates
11027280SIGNOR-82966
CAMK2AEGFRSer1120QPLNPAPsRDPHYQDphosphorylation
down-regulates activity
10347170SIGNOR-250623
CAMK2AKRT18Ser53ISVSRSTsFRGGMGSphosphorylation
unknown
7523419SIGNOR-250633
CAMK2ACLCN3Ser109ERHRRINsKKKESAWphosphorylation
up-regulates activity
14754994SIGNOR-275863
CAMK2APDCSer54KEILRQMsSPQSRNGphosphorylation
unknown
11331285SIGNOR-250636
CAMK2ASYNGAP1Thr1077RGKSQQLtVSAAQKPphosphorylation
up-regulates activity
15358237SIGNOR-262691
CAMK2ASMAD2Ser240SDQQLNQsMDTGSPAphosphorylation
down-regulates
11027280SIGNOR-82970
CAMK2ANOS1Ser852SYKVRFNsVSSYSDSphosphorylation
down-regulates activity
10400690SIGNOR-250635
CAMK2AETS2Ser310LDVQRVPsFESFEDDphosphorylation
down-regulates
19182667SIGNOR-183600
CAMK2ACYLDSer362FYTLNGSsVDSQPQSphosphorylation
up-regulates activity
24614225SIGNOR-266442
CAMK2AHRH1Ser398WKRLRSHsRQYVSGLphosphorylation
down-regulates
15107581SIGNOR-124344
CAMK2ALIPESer855EPMRRSVsEAALAQPphosphorylation
down-regulates
9636039SIGNOR-58251
CAMK2AGFAPSer17ARRSYVSsGEMMVGGphosphorylation
down-regulates activity
7822264SIGNOR-250627
CAMK2ADLG1Ser232ITLERGNsGLGFSIAphosphorylation
down-regulates activity
12933808SIGNOR-250618
CAMK2ASRFThr160NKLRRYTtFSKRKTGphosphorylation
up-regulates activity
10753652SIGNOR-250639
CAMK2AGRIN2BSer1303NKLRRQHsYDTFVDLphosphorylation
up-regulates activity
8940188SIGNOR-250630
CAMK2AGFAPSer13ITSAARRsYVSSGEMphosphorylation
down-regulates activity
7822264SIGNOR-250626
CAMK2AETS1Ser257DSFESIEsYDSCDRLphosphorylation
down-regulates
12475968SIGNOR-96334
CAMK2ACYLDSer362FYTLNGSsVDSQPQSphosphorylation
up-regulates activity
24614225SIGNOR-266434
CAMK2ADAGLASer782APLATMEsLSDTESLphosphorylation
down-regulates activity
23502535SIGNOR-275539
CAMK2ARCHY1Thr154ICLEDIHtSRVVAHVphosphorylation
down-regulates
17568776SIGNOR-156068
CAMK2APKD2L1Thr591LKQGYNKtLLRLRLRphosphorylation
down-regulates activity
37193065SIGNOR-277798
CAMK2AFBXO43Ser192NLEKNIPsSASGFSRphosphorylation
up-regulates activity
16407128SIGNOR-260907
CAMK2ANOX5Ser521WTNRLYEsFKASDPLphosphorylation
up-regulates activity
21642394SIGNOR-276329
CAMK2APTTG1Thr66ATRKALGtVNRATEKphosphorylation
down-regulates quantity by destabilization
24781523SIGNOR-276377
CAMK2AEGFRSer1064SCPIKEDsFLQRYSSphosphorylation
down-regulates activity
10347170SIGNOR-250619
CAMK2ACAMK2AThr306LKGAILTtMLATRNFphosphorylation
down-regulates
1324926SIGNOR-17316
CAMK2ACAMK2AThr305KLKGAILtTMLATRNphosphorylation
down-regulates
1324926SIGNOR-17312
CAMK2AHOMERphosphorylation
down-regulates activity
18480293SIGNOR-264699
CAMK2AHOMER3Ser159EKLFRSQsADAPGPTphosphorylation
down-regulates activity
18480293SIGNOR-262685
CAMK2ACHATThr574VDNIRSAtPEALAFVphosphorylation
up-regulates
12486117SIGNOR-96628
CAMK2ACD44Ser706LNGEASKsQEMVHLVphosphorylation
up-regulates activity
11463356SIGNOR-109502
CAMK2AID1Ser36GEVVRCLsEQSVAISphosphorylation
up-regulates activity
29079782SIGNOR-277367
CAMK2APTTG1Ser87PLKQKQPsFSAKKMTphosphorylation
down-regulates quantity by destabilization
24781523SIGNOR-276381
CAMK2ACREB1Ser142RKILNDLsSDAPGVPphosphorylation
down-regulates
9668047SIGNOR-59137
CAMK2APTK2Ser843DVRLSRGsIDREDGSphosphorylation
up-regulates
15845548SIGNOR-135631
CAMK2ALRRC7Ser1439IQTKGQRsMDGYPEQphosphorylation
unknown
11160423SIGNOR-250634
CAMK2AGABBR1Ser868ITRGEWQsEAQDTMKphosphorylation
down-regulates
20643921SIGNOR-166846
CAMK2ANOX5Thr540KRLSRSVtMRKSQRSphosphorylation
unknown
21642394SIGNOR-276330
CAMK2ANOX5Ser544RSVTMRKsQRSSKGSphosphorylation
unknown
21642394SIGNOR-276331
CAMK2AETS1Ser285QRVPSYDsFDSEDYPphosphorylation
down-regulates
12475968SIGNOR-96342
CAMK2AETS2Ser246FPKSRLSsVSVTYCSphosphorylation
down-regulates
19182667SIGNOR-183596
CAMK2ASCN8ASer641RRSVKRNsTVDCNGVphosphorylation
up-regulates activity
32611770SIGNOR-275785
CAMK2ANCOR2Ser2426ASGDRPPsVSSVHSEphosphorylation
down-regulates
22888005SIGNOR-191773
CAMK2ASCN8ASer561PFLSRHNsKSSIFSFphosphorylation
up-regulates activity
32611770SIGNOR-275784
CAMK2AGFAPSer393NLQIRETsLDTKSVSphosphorylation
down-regulates activity
7822264SIGNOR-250629
CAMK2AHOMER3Ser176ERLKKMLsEGSVGEVphosphorylation
down-regulates activity
18480293SIGNOR-262686
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CAMK2Aphosphorylation
up-regulates
SCN8A
PThr642
phosphorylation
up-regulates
SCN8A32611770SIGNOR-275786
CAMK2Aphosphorylation
up-regulates
DAGLA
PSer808
phosphorylation
down-regulates
DAGLA23502535SIGNOR-275540
CAMK2Aphosphorylation
up-regulates
CACNA1H
PSer2137
phosphorylation
down-regulates
CACNA1H38001892SIGNOR-277871
CAMK2Aphosphorylation
up-regulates
CAMK2A
PSer314
phosphorylation
down-regulates
CAMK2A1324926SIGNOR-17308
CAMK2Aphosphorylation
up-regulates
STMN1
PSer16
phosphorylation
down-regulates
STMN116982419SIGNOR-149640
CAMK2Aphosphorylation
up-regulates
STMN1
PSer16
phosphorylation
down-regulates
STMN19686569SIGNOR-59354
CAMK2Aphosphorylation
up-regulates
GFAP
PSer38
phosphorylation
down-regulates
GFAP7822264SIGNOR-250628
CAMK2Aphosphorylation
up-regulates
MAPT
PSer552
phosphorylation
down-regulates
MAPT10090741SIGNOR-249316
CAMK2Aphosphorylation
up-regulates
ETS1
PSer282
phosphorylation
down-regulates
ETS112475968SIGNOR-96338
CAMK2Aphosphorylation
up-regulates
MAPT
PThr548
phosphorylation
down-regulates
MAPT10090741SIGNOR-249315
CAMK2Aphosphorylation
up-regulates
HOMER3
PSer120
phosphorylation
down-regulates
HOMER318480293SIGNOR-262684
CAMK2Aphosphorylation
up-regulates
PTTG1
PSer89
phosphorylation
down-regulates
PTTG124781523SIGNOR-276383
CAMK2Aphosphorylation
up-regulates
CACNA1S
PSer1575
phosphorylation
up-regulates
CACNA1S20937870SIGNOR-263113
CAMK2Aphosphorylation
up-regulates
RCHY1
PSer155
phosphorylation
down-regulates
RCHY117568776SIGNOR-156064
CAMK2Aphosphorylation
up-regulates
SYNGAP1
PSer780
phosphorylation
up-regulates
SYNGAP114970204SIGNOR-262690
CAMK2Aphosphorylation
up-regulates
CYLD
PSer772
phosphorylation
up-regulates
CYLD24614225SIGNOR-266433
CAMK2Aphosphorylation
up-regulates
PDC
PSer73
phosphorylation
down-regulates
PDC11331285SIGNOR-250637
CAMK2Aphosphorylation
up-regulates
PTTG1
PSer31
phosphorylation
down-regulates
PTTG124781523SIGNOR-276382
CAMK2Aphosphorylation
up-regulates
RIMS1
PSer242
phosphorylation
up-regulates
RIMS112871946SIGNOR-103886
CAMK2Aphosphorylation
up-regulates
NOX5
PSer547
phosphorylation
down-regulates
NOX521642394SIGNOR-276332
CAMK2Aphosphorylation
up-regulates
ATP2A2
PSer38
phosphorylation
up-regulates
ATP2A27929371SIGNOR-250616
CAMK2Aphosphorylation
up-regulates
RIMS1
PSer288
phosphorylation
up-regulates
RIMS112871946SIGNOR-103890
CAMK2Aphosphorylation
up-regulates
SCN5A
PSer571
phosphorylation
up-regulates
SCN5A33410863SIGNOR-275771
CAMK2Aphosphorylation
up-regulates
SRF
PSer103
phosphorylation
up-regulates
SRF10753652SIGNOR-250638
CAMK2Aphosphorylation
up-regulates
ETS2
PSer313
phosphorylation
down-regulates
ETS219182667SIGNOR-183604
CAMK2Aphosphorylation
up-regulates
ALOX5
PSer272
phosphorylation
up-regulates
ALOX518978352SIGNOR-264408
CAMK2Aphosphorylation
up-regulates
ITPKA
PThr311
phosphorylation
up-regulates
ITPKA9155020SIGNOR-48387
CAMK2Aphosphorylation
up-regulates
GFPT1
PSer261
phosphorylation
up-regulates
GFPT117941647SIGNOR-158486
CAMK2Aphosphorylation
up-regulates
CD44
PSer706
phosphorylation
up-regulates
CD449580567SIGNOR-57376
CAMK2Aphosphorylation
up-regulates
ITGB1BP1
PThr38
phosphorylation
up-regulates
ITGB1BP19813144SIGNOR-250632
CAMK2Aphosphorylation
up-regulates
NOX5
PSer548
phosphorylation
down-regulates
NOX521642394SIGNOR-276333
CAMK2Aphosphorylation
up-regulates
CYLD
PSer772
phosphorylation
up-regulates
CYLD24614225SIGNOR-266441
CAMK2Aphosphorylation
up-regulates
MAPT
PSer579
phosphorylation
down-regulates
MAPT10090741SIGNOR-249314
CAMK2Aphosphorylation
up-regulates
SYNGAP1
PSer1073
phosphorylation
up-regulates
SYNGAP114970204SIGNOR-262687
CAMK2Aphosphorylation
up-regulates
PEA15
PSer116
phosphorylation
up-regulates
PEA1515916534SIGNOR-137614
CAMK2Aphosphorylation
up-regulates
SCN5A
PSer516
phosphorylation
up-regulates
SCN5A33410863SIGNOR-275770
CAMK2Aphosphorylation
up-regulates
SYNGAP1
PSer1138
phosphorylation
up-regulates
SYNGAP114970204SIGNOR-262688
CAMK2Aphosphorylation
up-regulates
OPRM1
PSer270
phosphorylation
down-regulates
OPRM110908300SIGNOR-79682
CAMK2Aphosphorylation
up-regulates
GRIA4
PSer862
phosphorylation
up-regulates
GRIA412536214SIGNOR-97546
CAMK2Aphosphorylation
up-regulates
CREB1
PSer142
phosphorylation
down-regulates
CREB111013247SIGNOR-82501
CAMK2Aphosphorylation
up-regulates
GLO1
PThr107
phosphorylation
up-regulates
GLO132966793SIGNOR-273553
CAMK2Aphosphorylation
up-regulates
CEBPB
PSer325
phosphorylation
up-regulates
CEBPB1314426SIGNOR-250617
CAMK2Aphosphorylation
up-regulates
CAMK2A
PThr286
phosphorylation
up-regulates
CAMK2A1849884SIGNOR-21797
CAMK2Aphosphorylation
up-regulates
TH
PSer19
phosphorylation
up-regulates
TH1680128SIGNOR-20912
CAMK2Aphosphorylation
up-regulates
OPRM1
PThr372
phosphorylation
down-regulates
OPRM110908300SIGNOR-79686
CAMK2Aphosphorylation
up-regulates
PKD2L1
PThr591
phosphorylation
down-regulates
PKD2L137193065SIGNOR-277812
CAMK2Aphosphorylation
up-regulates
HSF1
PSer230
phosphorylation
up-regulates
HSF111447121SIGNOR-250631
CAMK2Aphosphorylation
up-regulates
SYNGAP1
PSer779
phosphorylation
up-regulates
SYNGAP114970204SIGNOR-262689
CAMK2Aphosphorylation
up-regulates
CALD1
PSer656
phosphorylation
down-regulates
CALD12170388SIGNOR-22635
CAMK2Aphosphorylation
up-regulates
CREB1
PSer142
phosphorylation
down-regulates
CREB111970864SIGNOR-117344
CAMK2Aphosphorylation
up-regulates
CACNA1B
PSer2120
phosphorylation
down-regulates
CACNA1B16982421SIGNOR-149684
CAMK2Aphosphorylation
up-regulates
SLN
PThr5
phosphorylation
down-regulates
SLN23455424SIGNOR-264778
CAMK2Aphosphorylation
up-regulates
EGFR
PSer1166
phosphorylation
down-regulates
EGFR10347170SIGNOR-250624
CAMK2Aphosphorylation
up-regulates
EGFR
PSer768
phosphorylation
down-regulates
EGFR10347170SIGNOR-250625
CAMK2Aphosphorylation
up-regulates
EGFR
PSer1081
phosphorylation
down-regulates
EGFR10347170SIGNOR-250622
CAMK2Aphosphorylation
up-regulates
SMAD2
PSer260
phosphorylation
down-regulates
SMAD211027280SIGNOR-82974
CAMK2Aphosphorylation
up-regulates
HRH1
PThr140
phosphorylation
down-regulates
HRH115107581SIGNOR-124348
CAMK2Aphosphorylation
up-regulates
SCN5A
PThr594
phosphorylation
up-regulates
SCN5A33410863SIGNOR-275772
CAMK2Aphosphorylation
up-regulates
OPRM1
PSer268
phosphorylation
down-regulates
OPRM110908300SIGNOR-79678
CAMK2Aphosphorylation
up-regulates
ETS1
PSer251
phosphorylation
down-regulates
ETS112475968SIGNOR-96330
CAMK2Aphosphorylation
up-regulates
EGFR
PSer1071
phosphorylation
down-regulates
EGFR10347170SIGNOR-250621
CAMK2Aphosphorylation
up-regulates
DLGAP1
PSer356
phosphorylation
down-regulates
DLGAP123143515SIGNOR-276429
CAMK2Aphosphorylation
up-regulates
EGFR
PSer1070
phosphorylation
down-regulates
EGFR10347170SIGNOR-250620
CAMK2Aphosphorylation
up-regulates
CALD1
PSer643
phosphorylation
down-regulates
CALD12170388SIGNOR-22631
CAMK2Aphosphorylation
up-regulates
SMAD2
PSer110
phosphorylation
down-regulates
SMAD211027280SIGNOR-82966
CAMK2Aphosphorylation
up-regulates
EGFR
PSer1120
phosphorylation
down-regulates
EGFR10347170SIGNOR-250623
CAMK2Aphosphorylation
up-regulates
KRT18
PSer53
phosphorylation
down-regulates
KRT187523419SIGNOR-250633
CAMK2Aphosphorylation
up-regulates
CLCN3
PSer109
phosphorylation
up-regulates
CLCN314754994SIGNOR-275863
CAMK2Aphosphorylation
up-regulates
PDC
PSer54
phosphorylation
down-regulates
PDC11331285SIGNOR-250636
CAMK2Aphosphorylation
up-regulates
SYNGAP1
PThr1077
phosphorylation
up-regulates
SYNGAP115358237SIGNOR-262691
CAMK2Aphosphorylation
up-regulates
SMAD2
PSer240
phosphorylation
down-regulates
SMAD211027280SIGNOR-82970
CAMK2Aphosphorylation
up-regulates
NOS1
PSer852
phosphorylation
down-regulates
NOS110400690SIGNOR-250635
CAMK2Aphosphorylation
up-regulates
ETS2
PSer310
phosphorylation
down-regulates
ETS219182667SIGNOR-183600
CAMK2Aphosphorylation
up-regulates
CYLD
PSer362
phosphorylation
up-regulates
CYLD24614225SIGNOR-266442
CAMK2Aphosphorylation
up-regulates
HRH1
PSer398
phosphorylation
down-regulates
HRH115107581SIGNOR-124344
CAMK2Aphosphorylation
up-regulates
LIPE
PSer855
phosphorylation
down-regulates
LIPE9636039SIGNOR-58251
CAMK2Aphosphorylation
up-regulates
GFAP
PSer17
phosphorylation
down-regulates
GFAP7822264SIGNOR-250627
CAMK2Aphosphorylation
up-regulates
DLG1
PSer232
phosphorylation
down-regulates
DLG112933808SIGNOR-250618
CAMK2Aphosphorylation
up-regulates
SRF
PThr160
phosphorylation
up-regulates
SRF10753652SIGNOR-250639
CAMK2Aphosphorylation
up-regulates
GRIN2B
PSer1303
phosphorylation
up-regulates
GRIN2B8940188SIGNOR-250630
CAMK2Aphosphorylation
up-regulates
GFAP
PSer13
phosphorylation
down-regulates
GFAP7822264SIGNOR-250626
CAMK2Aphosphorylation
up-regulates
ETS1
PSer257
phosphorylation
down-regulates
ETS112475968SIGNOR-96334
CAMK2Aphosphorylation
up-regulates
CYLD
PSer362
phosphorylation
up-regulates
CYLD24614225SIGNOR-266434
CAMK2Aphosphorylation
up-regulates
DAGLA
PSer782
phosphorylation
down-regulates
DAGLA23502535SIGNOR-275539
CAMK2Aphosphorylation
up-regulates
RCHY1
PThr154
phosphorylation
down-regulates
RCHY117568776SIGNOR-156068
CAMK2Aphosphorylation
up-regulates
PKD2L1
PThr591
phosphorylation
down-regulates
PKD2L137193065SIGNOR-277798
CAMK2Aphosphorylation
up-regulates
FBXO43
PSer192
phosphorylation
up-regulates
FBXO4316407128SIGNOR-260907
CAMK2Aphosphorylation
up-regulates
NOX5
PSer521
phosphorylation
up-regulates
NOX521642394SIGNOR-276329
CAMK2Aphosphorylation
up-regulates
PTTG1
PThr66
phosphorylation
down-regulates
PTTG124781523SIGNOR-276377
CAMK2Aphosphorylation
up-regulates
EGFR
PSer1064
phosphorylation
down-regulates
EGFR10347170SIGNOR-250619
CAMK2Aphosphorylation
up-regulates
CAMK2A
PThr306
phosphorylation
down-regulates
CAMK2A1324926SIGNOR-17316
CAMK2Aphosphorylation
up-regulates
CAMK2A
PThr305
phosphorylation
down-regulates
CAMK2A1324926SIGNOR-17312
CAMK2Aphosphorylation
up-regulates
HOMER3
PSer159
phosphorylation
down-regulates
HOMER318480293SIGNOR-262685
CAMK2Aphosphorylation
up-regulates
CHAT
PThr574
phosphorylation
up-regulates
CHAT12486117SIGNOR-96628
CAMK2Aphosphorylation
up-regulates
CD44
PSer706
phosphorylation
up-regulates
CD4411463356SIGNOR-109502
CAMK2Aphosphorylation
up-regulates
ID1
PSer36
phosphorylation
up-regulates
ID129079782SIGNOR-277367
CAMK2Aphosphorylation
up-regulates
PTTG1
PSer87
phosphorylation
down-regulates
PTTG124781523SIGNOR-276381
CAMK2Aphosphorylation
up-regulates
CREB1
PSer142
phosphorylation
down-regulates
CREB19668047SIGNOR-59137
CAMK2Aphosphorylation
up-regulates
PTK2
PSer843
phosphorylation
up-regulates
PTK215845548SIGNOR-135631
CAMK2Aphosphorylation
up-regulates
LRRC7
PSer1439
phosphorylation
down-regulates
LRRC711160423SIGNOR-250634
CAMK2Aphosphorylation
up-regulates
GABBR1
PSer868
phosphorylation
down-regulates
GABBR120643921SIGNOR-166846
CAMK2Aphosphorylation
up-regulates
NOX5
PThr540
phosphorylation
down-regulates
NOX521642394SIGNOR-276330
CAMK2Aphosphorylation
up-regulates
NOX5
PSer544
phosphorylation
down-regulates
NOX521642394SIGNOR-276331
CAMK2Aphosphorylation
up-regulates
ETS1
PSer285
phosphorylation
down-regulates
ETS112475968SIGNOR-96342
CAMK2Aphosphorylation
up-regulates
ETS2
PSer246
phosphorylation
down-regulates
ETS219182667SIGNOR-183596
CAMK2Aphosphorylation
up-regulates
SCN8A
PSer641
phosphorylation
up-regulates
SCN8A32611770SIGNOR-275785
CAMK2Aphosphorylation
up-regulates
NCOR2
PSer2426
phosphorylation
down-regulates
NCOR222888005SIGNOR-191773
CAMK2Aphosphorylation
up-regulates
SCN8A
PSer561
phosphorylation
up-regulates
SCN8A32611770SIGNOR-275784
CAMK2Aphosphorylation
up-regulates
GFAP
PSer393
phosphorylation
down-regulates
GFAP7822264SIGNOR-250629
CAMK2Aphosphorylation
up-regulates
HOMER3
PSer176
phosphorylation
down-regulates
HOMER318480293SIGNOR-262686
Regulator Mechanism/Effect Target SIGNOR-ID
CAMK2Aphosphorylation

up-regulates activity
SCN8ASIGNOR-275786
CAMK2Aphosphorylation

down-regulates activity
DAGLASIGNOR-275540
CAMK2Aphosphorylation

down-regulates activity
CACNA1HSIGNOR-277871
CAMK2Aphosphorylation
img/direct_inhibition.png
down-regulates
CAMK2ASIGNOR-17308
CAMK2Aphosphorylation
img/direct_inhibition.png
down-regulates
STMN1SIGNOR-149640
CAMK2Aphosphorylation
img/direct_inhibition.png
down-regulates
STMN1SIGNOR-59354
CAMK2Aphosphorylation

down-regulates activity
GFAPSIGNOR-250628
CAMK2Aphosphorylation

down-regulates activity
MAPTSIGNOR-249316
CAMK2Aphosphorylation
img/direct_inhibition.png
down-regulates
ETS1SIGNOR-96338
CAMK2Aphosphorylation

down-regulates activity
MAPTSIGNOR-249315
CAMK2Aphosphorylation

down-regulates activity
HOMER3SIGNOR-262684
CAMK2Aphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization
PTTG1SIGNOR-276383
CAMK2Aphosphorylation

up-regulates activity
CACNA1SSIGNOR-263113
CAMK2Aphosphorylation
img/direct_inhibition.png
down-regulates
RCHY1SIGNOR-156064
CAMK2Aphosphorylation

up-regulates activity
SYNGAP1SIGNOR-262690
CAMK2Aphosphorylation

up-regulates activity
CYLDSIGNOR-266433
CAMK2Aphosphorylation

unknown
PDCSIGNOR-250637
CAMK2Aphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization
PTTG1SIGNOR-276382
CAMK2Aphosphorylation

up-regulates
RIMS1SIGNOR-103886
CAMK2Aphosphorylation

unknown
NOX5SIGNOR-276332
CAMK2Aphosphorylation

up-regulates activity
ATP2A2SIGNOR-250616
CAMK2Aphosphorylation

up-regulates
RIMS1SIGNOR-103890
CAMK2Aphosphorylation

up-regulates activity
SCN5ASIGNOR-275771
CAMK2Aphosphorylation

up-regulates activity
SRFSIGNOR-250638
CAMK2Aphosphorylation
img/direct_inhibition.png
down-regulates
ETS2SIGNOR-183604
CAMK2Aphosphorylation

up-regulates activity
ALOX5SIGNOR-264408
CAMK2Aphosphorylation

up-regulates
ITPKASIGNOR-48387
CAMK2Aphosphorylation

up-regulates
GFPT1SIGNOR-158486
CAMK2Aphosphorylation

up-regulates
CD44SIGNOR-57376
CAMK2Aphosphorylation

up-regulates activity
ITGB1BP1SIGNOR-250632
CAMK2Aphosphorylation

unknown
NOX5SIGNOR-276333
CAMK2Aphosphorylation

down-regulates activity
ANKS1BSIGNOR-264231
CAMK2Aphosphorylation

up-regulates activity
CYLDSIGNOR-266441
CAMK2Aphosphorylation

down-regulates activity
MAPTSIGNOR-249314
CAMK2Aphosphorylation

up-regulates activity
SYNGAP1SIGNOR-262687
CAMK2Aphosphorylation

up-regulates
PEA15SIGNOR-137614
CAMK2Aphosphorylation

up-regulates activity
SCN5ASIGNOR-275770
CAMK2Aphosphorylation

up-regulates activity
SYNGAP1SIGNOR-262688
CAMK2Aphosphorylation
img/direct_inhibition.png
down-regulates
OPRM1SIGNOR-79682
CAMK2Aphosphorylation

up-regulates
GRIA4SIGNOR-97546
CAMK2Aphosphorylation
img/direct_inhibition.png
down-regulates
CREB1SIGNOR-82501
CAMK2Aphosphorylation

up-regulates activity
GLO1SIGNOR-273553
CAMK2Aphosphorylation

up-regulates activity
CEBPBSIGNOR-250617
CAMK2Aphosphorylation

up-regulates
CAMK2ASIGNOR-21797
CAMK2Aphosphorylation

up-regulates
THSIGNOR-20912
CAMK2Aphosphorylation
img/direct_inhibition.png
down-regulates
OPRM1SIGNOR-79686
CAMK2Aphosphorylation
img/direct_inhibition.png
down-regulates
MAPTSIGNOR-255490
CAMK2Aphosphorylation

down-regulates activity
PKD2L1SIGNOR-277812
CAMK2Aphosphorylation

up-regulates activity
HSF1SIGNOR-250631
CAMK2Aphosphorylation

up-regulates
AMPASIGNOR-270230
CAMK2Aphosphorylation

up-regulates activity
SYNGAP1SIGNOR-262689
CAMK2Aphosphorylation
img/direct_inhibition.png
down-regulates
CALD1SIGNOR-22635
CAMK2Aphosphorylation
img/direct_inhibition.png
down-regulates
CREB1SIGNOR-117344
CAMK2Aphosphorylation
img/direct_inhibition.png
down-regulates
CACNA1BSIGNOR-149684
CAMK2Aphosphorylation

down-regulates activity
SLNSIGNOR-264778
CAMK2Aphosphorylation

down-regulates activity
EGFRSIGNOR-250624
CAMK2Aphosphorylation

down-regulates activity
EGFRSIGNOR-250625
CAMK2Aphosphorylation

down-regulates activity
EGFRSIGNOR-250622
CAMK2Aphosphorylation
img/direct_inhibition.png
down-regulates
SMAD2SIGNOR-82974
CAMK2Aphosphorylation
img/direct_inhibition.png
down-regulates
HRH1SIGNOR-124348
CAMK2Aphosphorylation

up-regulates activity
SCN5ASIGNOR-275772
CAMK2Aphosphorylation
img/direct_inhibition.png
down-regulates
OPRM1SIGNOR-79678
CAMK2Aphosphorylation
img/direct_inhibition.png
down-regulates
ETS1SIGNOR-96330
CAMK2Aphosphorylation

down-regulates activity
EGFRSIGNOR-250621
CAMK2Aphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization
DLGAP1SIGNOR-276429
CAMK2Aphosphorylation

down-regulates activity
EGFRSIGNOR-250620
CAMK2Aphosphorylation
img/direct_inhibition.png
down-regulates
CALD1SIGNOR-22631
CAMK2Aphosphorylation
img/direct_inhibition.png
down-regulates
SMAD2SIGNOR-82966
CAMK2Aphosphorylation

down-regulates activity
EGFRSIGNOR-250623
CAMK2Aphosphorylation

unknown
KRT18SIGNOR-250633
CAMK2Aphosphorylation

up-regulates activity
CLCN3SIGNOR-275863
CAMK2Aphosphorylation

unknown
PDCSIGNOR-250636
CAMK2Aphosphorylation

up-regulates activity
SYNGAP1SIGNOR-262691
CAMK2Aphosphorylation
img/direct_inhibition.png
down-regulates
SMAD2SIGNOR-82970
CAMK2Aphosphorylation

down-regulates activity
NOS1SIGNOR-250635
CAMK2Aphosphorylation
img/direct_inhibition.png
down-regulates
ETS2SIGNOR-183600
CAMK2Aphosphorylation

up-regulates activity
CYLDSIGNOR-266442
CAMK2Aphosphorylation
img/direct_inhibition.png
down-regulates
HRH1SIGNOR-124344
CAMK2Aphosphorylation
img/direct_inhibition.png
down-regulates
LIPESIGNOR-58251
CAMK2Aphosphorylation

down-regulates activity
GFAPSIGNOR-250627
CAMK2Aphosphorylation

down-regulates activity
DLG1SIGNOR-250618
CAMK2Aphosphorylation

up-regulates activity
SRFSIGNOR-250639
CAMK2Aphosphorylation

up-regulates activity
GRIN2BSIGNOR-250630
CAMK2Aphosphorylation

down-regulates activity
GFAPSIGNOR-250626
CAMK2Aphosphorylation
img/direct_inhibition.png
down-regulates
ETS1SIGNOR-96334
CAMK2Aphosphorylation

up-regulates activity
CYLDSIGNOR-266434
CAMK2Aphosphorylation

down-regulates activity
DAGLASIGNOR-275539
CAMK2Aphosphorylation
img/direct_inhibition.png
down-regulates
RCHY1SIGNOR-156068
CAMK2Aphosphorylation

down-regulates activity
PKD2L1SIGNOR-277798
CAMK2Aphosphorylation

up-regulates activity
FBXO43SIGNOR-260907
CAMK2Aphosphorylation

up-regulates activity
NOX5SIGNOR-276329
CAMK2Aphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization
PTTG1SIGNOR-276377
CAMK2Aphosphorylation

down-regulates activity
EGFRSIGNOR-250619
CAMK2Aphosphorylation
img/direct_inhibition.png
down-regulates
CAMK2ASIGNOR-17316
CAMK2Aphosphorylation
img/direct_inhibition.png
down-regulates
CAMK2ASIGNOR-17312
CAMK2Aphosphorylation

down-regulates activity
HOMERSIGNOR-264699
CAMK2Aphosphorylation

down-regulates activity
HOMER3SIGNOR-262685
CAMK2Aphosphorylation

up-regulates
CHATSIGNOR-96628
CAMK2Aphosphorylation

up-regulates activity
CD44SIGNOR-109502
CAMK2Aphosphorylation

up-regulates activity
ID1SIGNOR-277367
CAMK2Aphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization
PTTG1SIGNOR-276381
CAMK2Aphosphorylation
img/direct_inhibition.png
down-regulates
CREB1SIGNOR-59137
CAMK2Aphosphorylation

up-regulates
PTK2SIGNOR-135631
CAMK2Aphosphorylation

unknown
LRRC7SIGNOR-250634
CAMK2Aphosphorylation
img/direct_inhibition.png
down-regulates
GABBR1SIGNOR-166846
CAMK2Aphosphorylation

unknown
NOX5SIGNOR-276330
CAMK2Aphosphorylation

unknown
NOX5SIGNOR-276331
CAMK2Aphosphorylation
img/direct_inhibition.png
down-regulates
ETS1SIGNOR-96342
CAMK2Aphosphorylation
img/direct_inhibition.png
down-regulates
ETS2SIGNOR-183596
CAMK2Aphosphorylation

up-regulates activity
SCN8ASIGNOR-275785
CAMK2Aphosphorylation
img/direct_inhibition.png
down-regulates
NCOR2SIGNOR-191773
CAMK2Aphosphorylation

up-regulates activity
SCN8ASIGNOR-275784
CAMK2Aphosphorylation

down-regulates activity
GFAPSIGNOR-250629
CAMK2Aphosphorylation

down-regulates activity
HOMER3SIGNOR-262686