| Name | CAMK2A |
| ID | Q9UQM7 |
| Role | kinase |
| Enzymatic Domains |
Protein kinase 13-271 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CAMK2A | SCN8A | Thr642 | RSVKRNStVDCNGVV | phosphorylation up-regulates activity | 32611770 | SIGNOR-275786 |
| CAMK2A | DAGLA | Ser808 | RSIRGSPsLHAVLER | phosphorylation down-regulates activity | 23502535 | SIGNOR-275540 |
| CAMK2A | CACNA1H | Ser2137 | RDLRRLYsVDAQGFL | phosphorylation down-regulates activity | 38001892 | SIGNOR-277871 |
| CAMK2A | CAMK2A | Ser314 | MLATRNFsGGKSGGN | phosphorylation down-regulates | 1324926 | SIGNOR-17308 |
| CAMK2A | STMN1 | Ser16 | KELEKRAsGQAFELI | phosphorylation down-regulates | 16982419 | SIGNOR-149640 |
| CAMK2A | STMN1 | Ser16 | KELEKRAsGQAFELI | phosphorylation down-regulates | 9686569 | SIGNOR-59354 |
| CAMK2A | GFAP | Ser38 | LGPGTRLsLARMPPP | phosphorylation down-regulates activity | 7822264 | SIGNOR-250628 |
| CAMK2A | MAPT | Ser552 | VVRTPPKsPSSAKSR | phosphorylation down-regulates activity | 10090741 | SIGNOR-249316 |
| CAMK2A | ETS1 | Ser282 | NSLQRVPsYDSFDSE | phosphorylation down-regulates | 12475968 | SIGNOR-96338 |
| CAMK2A | MAPT | Thr548 | KKVAVVRtPPKSPSS | phosphorylation down-regulates activity | 10090741 | SIGNOR-249315 |
| CAMK2A | HOMER3 | Ser120 | ARLAREKsQDGGELT | phosphorylation down-regulates activity | 18480293 | SIGNOR-262684 |
| CAMK2A | PTTG1 | Ser89 | KQKQPSFsAKKMTEK | phosphorylation down-regulates quantity by destabilization | 24781523 | SIGNOR-276383 |
| CAMK2A | CACNA1S | Ser1575 | PEICRTVsGDLAAEE | phosphorylation up-regulates activity | 20937870 | SIGNOR-263113 |
| CAMK2A | RCHY1 | Ser155 | CLEDIHTsRVVAHVL | phosphorylation down-regulates | 17568776 | SIGNOR-156064 |
| CAMK2A | SYNGAP1 | Ser780 | MARGLNSsMDMARLP | phosphorylation up-regulates activity | 14970204 | SIGNOR-262690 |
| CAMK2A | CYLD | Ser772 | LFKKIFPsLELNITD | phosphorylation up-regulates activity | 24614225 | SIGNOR-266433 |
| CAMK2A | PDC | Ser73 | ERVSRKMsIQEYELI | phosphorylation unknown | 11331285 | SIGNOR-250637 |
| CAMK2A | PTTG1 | Ser31 | LKLGSGPsIKALDGR | phosphorylation down-regulates quantity by destabilization | 24781523 | SIGNOR-276382 |
| CAMK2A | RIMS1 | Ser242 | PSAPPDRsKGAEPSQ | phosphorylation up-regulates | 12871946 | SIGNOR-103886 |
| CAMK2A | NOX5 | Ser547 | TMRKSQRsSKGSEIL | phosphorylation unknown | 21642394 | SIGNOR-276332 |
| CAMK2A | ATP2A2 | Ser38 | KLKERWGsNELPAEE | phosphorylation up-regulates activity | 7929371 | SIGNOR-250616 |
| CAMK2A | RIMS1 | Ser288 | NGKGALKsERKRVPK | phosphorylation up-regulates | 12871946 | SIGNOR-103890 |
| CAMK2A | SCN5A | Ser571 | PWPLRRTsAQGQPSP | phosphorylation up-regulates activity | 33410863 | SIGNOR-275771 |
| CAMK2A | SRF | Ser103 | RGLKRSLsEMEIGMV | phosphorylation up-regulates activity | 10753652 | SIGNOR-250638 |
| CAMK2A | ETS2 | Ser313 | QRVPSFEsFEDDCSQ | phosphorylation down-regulates | 19182667 | SIGNOR-183604 |
| CAMK2A | ALOX5 | Ser272 | CSLERQLsLEQEVQQ | phosphorylation up-regulates activity | 18978352 | SIGNOR-264408 |
| CAMK2A | ITPKA | Thr311 | EHAQRAVtKPRYMQW | phosphorylation up-regulates | 9155020 | SIGNOR-48387 |
| CAMK2A | GFPT1 | Ser261 | CNLSRVDsTTCLFPV | phosphorylation up-regulates | 17941647 | SIGNOR-158486 |
| CAMK2A | CD44 | Ser706 | LNGEASKsQEMVHLV | phosphorylation up-regulates | 9580567 | SIGNOR-57376 |
| CAMK2A | ITGB1BP1 | Thr38 | GGLSRSStVASLDTD | phosphorylation up-regulates activity | 9813144 | SIGNOR-250632 |
| CAMK2A | NOX5 | Ser548 | MRKSQRSsKGSEILL | phosphorylation unknown | 21642394 | SIGNOR-276333 |
| CAMK2A | ANKS1B | – | phosphorylation down-regulates activity | 27477489 | SIGNOR-264231 | |
| CAMK2A | CYLD | Ser772 | LFKKIFPsLELNITD | phosphorylation up-regulates activity | 24614225 | SIGNOR-266441 |
| CAMK2A | MAPT | Ser579 | NVKSKIGsTENLKHQ | phosphorylation down-regulates activity | 10090741 | SIGNOR-249314 |
| CAMK2A | SYNGAP1 | Ser1073 | PPLQRGKsQQLTVSA | phosphorylation up-regulates activity | 14970204 | SIGNOR-262687 |
| CAMK2A | PEA15 | Ser116 | KDIIRQPsEEEIIKL | phosphorylation up-regulates | 15916534 | SIGNOR-137614 |
| CAMK2A | SCN5A | Ser516 | LSLTRGLsRTSMKPR | phosphorylation up-regulates activity | 33410863 | SIGNOR-275770 |
| CAMK2A | SYNGAP1 | Ser1138 | PSITKQHsQTPSTLN | phosphorylation up-regulates activity | 14970204 | SIGNOR-262688 |
| CAMK2A | OPRM1 | Ser270 | SVRMLSGsKEKDRNL | phosphorylation down-regulates | 10908300 | SIGNOR-79682 |
| CAMK2A | GRIA4 | Ser862 | IRNKARLsITGSVGE | phosphorylation up-regulates | 12536214 | SIGNOR-97546 |
| CAMK2A | CREB1 | Ser142 | RKILNDLsSDAPGVP | phosphorylation down-regulates | 11013247 | SIGNOR-82501 |
| CAMK2A | GLO1 | Thr107 | ELTHNWGtEDDETQS | phosphorylation up-regulates activity | 32966793 | SIGNOR-273553 |
| CAMK2A | CEBPB | Ser325 | EQLSRELsTLRNLFK | phosphorylation up-regulates activity | 1314426 | SIGNOR-250617 |
| CAMK2A | CAMK2A | Thr286 | SCMHRQEtVDCLKKF | phosphorylation up-regulates | 1849884 | SIGNOR-21797 |
| CAMK2A | TH | Ser19 | KGFRRAVsELDAKQA | phosphorylation up-regulates | 1680128 | SIGNOR-20912 |
| CAMK2A | OPRM1 | Thr372 | STRIRQNtRDHPSTA | phosphorylation down-regulates | 10908300 | SIGNOR-79686 |
| CAMK2A | MAPT | – | phosphorylation down-regulates | 15621017 | SIGNOR-255490 | |
| CAMK2A | PKD2L1 | Thr591 | LKQGYNKtLLRLRLR | phosphorylation down-regulates activity | 37193065 | SIGNOR-277812 |
| CAMK2A | HSF1 | Ser230 | PKYSRQFsLEHVHGS | phosphorylation up-regulates activity | 11447121 | SIGNOR-250631 |
| CAMK2A | AMPA | – | phosphorylation up-regulates | 12536214 | SIGNOR-270230 | |
| CAMK2A | SYNGAP1 | Ser779 | FMARGLNsSMDMARL | phosphorylation up-regulates activity | 14970204 | SIGNOR-262689 |
| CAMK2A | CALD1 | Ser656 | RAEFLNKsVQKSSGV | phosphorylation down-regulates | 2170388 | SIGNOR-22635 |
| CAMK2A | CREB1 | Ser142 | RKILNDLsSDAPGVP | phosphorylation down-regulates | 11970864 | SIGNOR-117344 |
| CAMK2A | CACNA1B | Ser2120 | ERRQPSSsSSEKQRF | phosphorylation down-regulates | 16982421 | SIGNOR-149684 |
| CAMK2A | SLN | Thr5 | tRELFLNF | phosphorylation down-regulates activity | 23455424 | SIGNOR-264778 |
| CAMK2A | EGFR | Ser1166 | QKGSHQIsLDNPDYQ | phosphorylation down-regulates activity | 10347170 | SIGNOR-250624 |
| CAMK2A | EGFR | Ser768 | DEAYVMAsVDNPHVC | phosphorylation down-regulates activity | 10347170 | SIGNOR-250625 |
| CAMK2A | EGFR | Ser1081 | TGALTEDsIDDTFLP | phosphorylation down-regulates activity | 10347170 | SIGNOR-250622 |
| CAMK2A | SMAD2 | Ser260 | TLSPVNHsLDLQPVT | phosphorylation down-regulates | 11027280 | SIGNOR-82974 |
| CAMK2A | HRH1 | Thr140 | LRYLKYRtKTRASAT | phosphorylation down-regulates | 15107581 | SIGNOR-124348 |
| CAMK2A | SCN5A | Thr594 | LHGKKNStVDCNGVV | phosphorylation up-regulates activity | 33410863 | SIGNOR-275772 |
| CAMK2A | OPRM1 | Ser268 | LKSVRMLsGSKEKDR | phosphorylation down-regulates | 10908300 | SIGNOR-79678 |
| CAMK2A | ETS1 | Ser251 | GKLGGQDsFESIESY | phosphorylation down-regulates | 12475968 | SIGNOR-96330 |
| CAMK2A | EGFR | Ser1071 | SFLQRYSsDPTGALT | phosphorylation down-regulates activity | 10347170 | SIGNOR-250621 |
| CAMK2A | DLGAP1 | Ser356 | KAMGDEDsGDSDTSP | phosphorylation down-regulates quantity by destabilization | 23143515 | SIGNOR-276429 |
| CAMK2A | EGFR | Ser1070 | DSFLQRYsSDPTGAL | phosphorylation down-regulates activity | 10347170 | SIGNOR-250620 |
| CAMK2A | CALD1 | Ser643 | CFTPKGSsLKIEERA | phosphorylation down-regulates | 2170388 | SIGNOR-22631 |
| CAMK2A | SMAD2 | Ser110 | SFSEQTRsLDGRLQV | phosphorylation down-regulates | 11027280 | SIGNOR-82966 |
| CAMK2A | EGFR | Ser1120 | QPLNPAPsRDPHYQD | phosphorylation down-regulates activity | 10347170 | SIGNOR-250623 |
| CAMK2A | KRT18 | Ser53 | ISVSRSTsFRGGMGS | phosphorylation unknown | 7523419 | SIGNOR-250633 |
| CAMK2A | CLCN3 | Ser109 | ERHRRINsKKKESAW | phosphorylation up-regulates activity | 14754994 | SIGNOR-275863 |
| CAMK2A | PDC | Ser54 | KEILRQMsSPQSRNG | phosphorylation unknown | 11331285 | SIGNOR-250636 |
| CAMK2A | SYNGAP1 | Thr1077 | RGKSQQLtVSAAQKP | phosphorylation up-regulates activity | 15358237 | SIGNOR-262691 |
| CAMK2A | SMAD2 | Ser240 | SDQQLNQsMDTGSPA | phosphorylation down-regulates | 11027280 | SIGNOR-82970 |
| CAMK2A | NOS1 | Ser852 | SYKVRFNsVSSYSDS | phosphorylation down-regulates activity | 10400690 | SIGNOR-250635 |
| CAMK2A | ETS2 | Ser310 | LDVQRVPsFESFEDD | phosphorylation down-regulates | 19182667 | SIGNOR-183600 |
| CAMK2A | CYLD | Ser362 | FYTLNGSsVDSQPQS | phosphorylation up-regulates activity | 24614225 | SIGNOR-266442 |
| CAMK2A | HRH1 | Ser398 | WKRLRSHsRQYVSGL | phosphorylation down-regulates | 15107581 | SIGNOR-124344 |
| CAMK2A | LIPE | Ser855 | EPMRRSVsEAALAQP | phosphorylation down-regulates | 9636039 | SIGNOR-58251 |
| CAMK2A | GFAP | Ser17 | ARRSYVSsGEMMVGG | phosphorylation down-regulates activity | 7822264 | SIGNOR-250627 |
| CAMK2A | DLG1 | Ser232 | ITLERGNsGLGFSIA | phosphorylation down-regulates activity | 12933808 | SIGNOR-250618 |
| CAMK2A | SRF | Thr160 | NKLRRYTtFSKRKTG | phosphorylation up-regulates activity | 10753652 | SIGNOR-250639 |
| CAMK2A | GRIN2B | Ser1303 | NKLRRQHsYDTFVDL | phosphorylation up-regulates activity | 8940188 | SIGNOR-250630 |
| CAMK2A | GFAP | Ser13 | ITSAARRsYVSSGEM | phosphorylation down-regulates activity | 7822264 | SIGNOR-250626 |
| CAMK2A | ETS1 | Ser257 | DSFESIEsYDSCDRL | phosphorylation down-regulates | 12475968 | SIGNOR-96334 |
| CAMK2A | CYLD | Ser362 | FYTLNGSsVDSQPQS | phosphorylation up-regulates activity | 24614225 | SIGNOR-266434 |
| CAMK2A | DAGLA | Ser782 | APLATMEsLSDTESL | phosphorylation down-regulates activity | 23502535 | SIGNOR-275539 |
| CAMK2A | RCHY1 | Thr154 | ICLEDIHtSRVVAHV | phosphorylation down-regulates | 17568776 | SIGNOR-156068 |
| CAMK2A | PKD2L1 | Thr591 | LKQGYNKtLLRLRLR | phosphorylation down-regulates activity | 37193065 | SIGNOR-277798 |
| CAMK2A | FBXO43 | Ser192 | NLEKNIPsSASGFSR | phosphorylation up-regulates activity | 16407128 | SIGNOR-260907 |
| CAMK2A | NOX5 | Ser521 | WTNRLYEsFKASDPL | phosphorylation up-regulates activity | 21642394 | SIGNOR-276329 |
| CAMK2A | PTTG1 | Thr66 | ATRKALGtVNRATEK | phosphorylation down-regulates quantity by destabilization | 24781523 | SIGNOR-276377 |
| CAMK2A | EGFR | Ser1064 | SCPIKEDsFLQRYSS | phosphorylation down-regulates activity | 10347170 | SIGNOR-250619 |
| CAMK2A | CAMK2A | Thr306 | LKGAILTtMLATRNF | phosphorylation down-regulates | 1324926 | SIGNOR-17316 |
| CAMK2A | CAMK2A | Thr305 | KLKGAILtTMLATRN | phosphorylation down-regulates | 1324926 | SIGNOR-17312 |
| CAMK2A | HOMER | – | phosphorylation down-regulates activity | 18480293 | SIGNOR-264699 | |
| CAMK2A | HOMER3 | Ser159 | EKLFRSQsADAPGPT | phosphorylation down-regulates activity | 18480293 | SIGNOR-262685 |
| CAMK2A | CHAT | Thr574 | VDNIRSAtPEALAFV | phosphorylation up-regulates | 12486117 | SIGNOR-96628 |
| CAMK2A | CD44 | Ser706 | LNGEASKsQEMVHLV | phosphorylation up-regulates activity | 11463356 | SIGNOR-109502 |
| CAMK2A | ID1 | Ser36 | GEVVRCLsEQSVAIS | phosphorylation up-regulates activity | 29079782 | SIGNOR-277367 |
| CAMK2A | PTTG1 | Ser87 | PLKQKQPsFSAKKMT | phosphorylation down-regulates quantity by destabilization | 24781523 | SIGNOR-276381 |
| CAMK2A | CREB1 | Ser142 | RKILNDLsSDAPGVP | phosphorylation down-regulates | 9668047 | SIGNOR-59137 |
| CAMK2A | PTK2 | Ser843 | DVRLSRGsIDREDGS | phosphorylation up-regulates | 15845548 | SIGNOR-135631 |
| CAMK2A | LRRC7 | Ser1439 | IQTKGQRsMDGYPEQ | phosphorylation unknown | 11160423 | SIGNOR-250634 |
| CAMK2A | GABBR1 | Ser868 | ITRGEWQsEAQDTMK | phosphorylation down-regulates | 20643921 | SIGNOR-166846 |
| CAMK2A | NOX5 | Thr540 | KRLSRSVtMRKSQRS | phosphorylation unknown | 21642394 | SIGNOR-276330 |
| CAMK2A | NOX5 | Ser544 | RSVTMRKsQRSSKGS | phosphorylation unknown | 21642394 | SIGNOR-276331 |
| CAMK2A | ETS1 | Ser285 | QRVPSYDsFDSEDYP | phosphorylation down-regulates | 12475968 | SIGNOR-96342 |
| CAMK2A | ETS2 | Ser246 | FPKSRLSsVSVTYCS | phosphorylation down-regulates | 19182667 | SIGNOR-183596 |
| CAMK2A | SCN8A | Ser641 | RRSVKRNsTVDCNGV | phosphorylation up-regulates activity | 32611770 | SIGNOR-275785 |
| CAMK2A | NCOR2 | Ser2426 | ASGDRPPsVSSVHSE | phosphorylation down-regulates | 22888005 | SIGNOR-191773 |
| CAMK2A | SCN8A | Ser561 | PFLSRHNsKSSIFSF | phosphorylation up-regulates activity | 32611770 | SIGNOR-275784 |
| CAMK2A | GFAP | Ser393 | NLQIRETsLDTKSVS | phosphorylation down-regulates activity | 7822264 | SIGNOR-250629 |
| CAMK2A | HOMER3 | Ser176 | ERLKKMLsEGSVGEV | phosphorylation down-regulates activity | 18480293 | SIGNOR-262686 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CAMK2A | phosphorylation up-regulates → | SCN8A PThr642 | phosphorylation up-regulates → | SCN8A | 32611770 | SIGNOR-275786 |
| CAMK2A | phosphorylation up-regulates → | DAGLA PSer808 | phosphorylation down-regulates ⊣ | DAGLA | 23502535 | SIGNOR-275540 |
| CAMK2A | phosphorylation up-regulates → | CACNA1H PSer2137 | phosphorylation down-regulates ⊣ | CACNA1H | 38001892 | SIGNOR-277871 |
| CAMK2A | phosphorylation up-regulates → | CAMK2A PSer314 | phosphorylation down-regulates ⊣ | CAMK2A | 1324926 | SIGNOR-17308 |
| CAMK2A | phosphorylation up-regulates → | STMN1 PSer16 | phosphorylation down-regulates ⊣ | STMN1 | 16982419 | SIGNOR-149640 |
| CAMK2A | phosphorylation up-regulates → | STMN1 PSer16 | phosphorylation down-regulates ⊣ | STMN1 | 9686569 | SIGNOR-59354 |
| CAMK2A | phosphorylation up-regulates → | GFAP PSer38 | phosphorylation down-regulates ⊣ | GFAP | 7822264 | SIGNOR-250628 |
| CAMK2A | phosphorylation up-regulates → | MAPT PSer552 | phosphorylation down-regulates ⊣ | MAPT | 10090741 | SIGNOR-249316 |
| CAMK2A | phosphorylation up-regulates → | ETS1 PSer282 | phosphorylation down-regulates ⊣ | ETS1 | 12475968 | SIGNOR-96338 |
| CAMK2A | phosphorylation up-regulates → | MAPT PThr548 | phosphorylation down-regulates ⊣ | MAPT | 10090741 | SIGNOR-249315 |
| CAMK2A | phosphorylation up-regulates → | HOMER3 PSer120 | phosphorylation down-regulates ⊣ | HOMER3 | 18480293 | SIGNOR-262684 |
| CAMK2A | phosphorylation up-regulates → | PTTG1 PSer89 | phosphorylation down-regulates ⊣ | PTTG1 | 24781523 | SIGNOR-276383 |
| CAMK2A | phosphorylation up-regulates → | CACNA1S PSer1575 | phosphorylation up-regulates → | CACNA1S | 20937870 | SIGNOR-263113 |
| CAMK2A | phosphorylation up-regulates → | RCHY1 PSer155 | phosphorylation down-regulates ⊣ | RCHY1 | 17568776 | SIGNOR-156064 |
| CAMK2A | phosphorylation up-regulates → | SYNGAP1 PSer780 | phosphorylation up-regulates → | SYNGAP1 | 14970204 | SIGNOR-262690 |
| CAMK2A | phosphorylation up-regulates → | CYLD PSer772 | phosphorylation up-regulates → | CYLD | 24614225 | SIGNOR-266433 |
| CAMK2A | phosphorylation up-regulates → | PDC PSer73 | phosphorylation down-regulates ⊣ | PDC | 11331285 | SIGNOR-250637 |
| CAMK2A | phosphorylation up-regulates → | PTTG1 PSer31 | phosphorylation down-regulates ⊣ | PTTG1 | 24781523 | SIGNOR-276382 |
| CAMK2A | phosphorylation up-regulates → | RIMS1 PSer242 | phosphorylation up-regulates → | RIMS1 | 12871946 | SIGNOR-103886 |
| CAMK2A | phosphorylation up-regulates → | NOX5 PSer547 | phosphorylation down-regulates ⊣ | NOX5 | 21642394 | SIGNOR-276332 |
| CAMK2A | phosphorylation up-regulates → | ATP2A2 PSer38 | phosphorylation up-regulates → | ATP2A2 | 7929371 | SIGNOR-250616 |
| CAMK2A | phosphorylation up-regulates → | RIMS1 PSer288 | phosphorylation up-regulates → | RIMS1 | 12871946 | SIGNOR-103890 |
| CAMK2A | phosphorylation up-regulates → | SCN5A PSer571 | phosphorylation up-regulates → | SCN5A | 33410863 | SIGNOR-275771 |
| CAMK2A | phosphorylation up-regulates → | SRF PSer103 | phosphorylation up-regulates → | SRF | 10753652 | SIGNOR-250638 |
| CAMK2A | phosphorylation up-regulates → | ETS2 PSer313 | phosphorylation down-regulates ⊣ | ETS2 | 19182667 | SIGNOR-183604 |
| CAMK2A | phosphorylation up-regulates → | ALOX5 PSer272 | phosphorylation up-regulates → | ALOX5 | 18978352 | SIGNOR-264408 |
| CAMK2A | phosphorylation up-regulates → | ITPKA PThr311 | phosphorylation up-regulates → | ITPKA | 9155020 | SIGNOR-48387 |
| CAMK2A | phosphorylation up-regulates → | GFPT1 PSer261 | phosphorylation up-regulates → | GFPT1 | 17941647 | SIGNOR-158486 |
| CAMK2A | phosphorylation up-regulates → | CD44 PSer706 | phosphorylation up-regulates → | CD44 | 9580567 | SIGNOR-57376 |
| CAMK2A | phosphorylation up-regulates → | ITGB1BP1 PThr38 | phosphorylation up-regulates → | ITGB1BP1 | 9813144 | SIGNOR-250632 |
| CAMK2A | phosphorylation up-regulates → | NOX5 PSer548 | phosphorylation down-regulates ⊣ | NOX5 | 21642394 | SIGNOR-276333 |
| CAMK2A | phosphorylation up-regulates → | CYLD PSer772 | phosphorylation up-regulates → | CYLD | 24614225 | SIGNOR-266441 |
| CAMK2A | phosphorylation up-regulates → | MAPT PSer579 | phosphorylation down-regulates ⊣ | MAPT | 10090741 | SIGNOR-249314 |
| CAMK2A | phosphorylation up-regulates → | SYNGAP1 PSer1073 | phosphorylation up-regulates → | SYNGAP1 | 14970204 | SIGNOR-262687 |
| CAMK2A | phosphorylation up-regulates → | PEA15 PSer116 | phosphorylation up-regulates → | PEA15 | 15916534 | SIGNOR-137614 |
| CAMK2A | phosphorylation up-regulates → | SCN5A PSer516 | phosphorylation up-regulates → | SCN5A | 33410863 | SIGNOR-275770 |
| CAMK2A | phosphorylation up-regulates → | SYNGAP1 PSer1138 | phosphorylation up-regulates → | SYNGAP1 | 14970204 | SIGNOR-262688 |
| CAMK2A | phosphorylation up-regulates → | OPRM1 PSer270 | phosphorylation down-regulates ⊣ | OPRM1 | 10908300 | SIGNOR-79682 |
| CAMK2A | phosphorylation up-regulates → | GRIA4 PSer862 | phosphorylation up-regulates → | GRIA4 | 12536214 | SIGNOR-97546 |
| CAMK2A | phosphorylation up-regulates → | CREB1 PSer142 | phosphorylation down-regulates ⊣ | CREB1 | 11013247 | SIGNOR-82501 |
| CAMK2A | phosphorylation up-regulates → | GLO1 PThr107 | phosphorylation up-regulates → | GLO1 | 32966793 | SIGNOR-273553 |
| CAMK2A | phosphorylation up-regulates → | CEBPB PSer325 | phosphorylation up-regulates → | CEBPB | 1314426 | SIGNOR-250617 |
| CAMK2A | phosphorylation up-regulates → | CAMK2A PThr286 | phosphorylation up-regulates → | CAMK2A | 1849884 | SIGNOR-21797 |
| CAMK2A | phosphorylation up-regulates → | TH PSer19 | phosphorylation up-regulates → | TH | 1680128 | SIGNOR-20912 |
| CAMK2A | phosphorylation up-regulates → | OPRM1 PThr372 | phosphorylation down-regulates ⊣ | OPRM1 | 10908300 | SIGNOR-79686 |
| CAMK2A | phosphorylation up-regulates → | PKD2L1 PThr591 | phosphorylation down-regulates ⊣ | PKD2L1 | 37193065 | SIGNOR-277812 |
| CAMK2A | phosphorylation up-regulates → | HSF1 PSer230 | phosphorylation up-regulates → | HSF1 | 11447121 | SIGNOR-250631 |
| CAMK2A | phosphorylation up-regulates → | SYNGAP1 PSer779 | phosphorylation up-regulates → | SYNGAP1 | 14970204 | SIGNOR-262689 |
| CAMK2A | phosphorylation up-regulates → | CALD1 PSer656 | phosphorylation down-regulates ⊣ | CALD1 | 2170388 | SIGNOR-22635 |
| CAMK2A | phosphorylation up-regulates → | CREB1 PSer142 | phosphorylation down-regulates ⊣ | CREB1 | 11970864 | SIGNOR-117344 |
| CAMK2A | phosphorylation up-regulates → | CACNA1B PSer2120 | phosphorylation down-regulates ⊣ | CACNA1B | 16982421 | SIGNOR-149684 |
| CAMK2A | phosphorylation up-regulates → | SLN PThr5 | phosphorylation down-regulates ⊣ | SLN | 23455424 | SIGNOR-264778 |
| CAMK2A | phosphorylation up-regulates → | EGFR PSer1166 | phosphorylation down-regulates ⊣ | EGFR | 10347170 | SIGNOR-250624 |
| CAMK2A | phosphorylation up-regulates → | EGFR PSer768 | phosphorylation down-regulates ⊣ | EGFR | 10347170 | SIGNOR-250625 |
| CAMK2A | phosphorylation up-regulates → | EGFR PSer1081 | phosphorylation down-regulates ⊣ | EGFR | 10347170 | SIGNOR-250622 |
| CAMK2A | phosphorylation up-regulates → | SMAD2 PSer260 | phosphorylation down-regulates ⊣ | SMAD2 | 11027280 | SIGNOR-82974 |
| CAMK2A | phosphorylation up-regulates → | HRH1 PThr140 | phosphorylation down-regulates ⊣ | HRH1 | 15107581 | SIGNOR-124348 |
| CAMK2A | phosphorylation up-regulates → | SCN5A PThr594 | phosphorylation up-regulates → | SCN5A | 33410863 | SIGNOR-275772 |
| CAMK2A | phosphorylation up-regulates → | OPRM1 PSer268 | phosphorylation down-regulates ⊣ | OPRM1 | 10908300 | SIGNOR-79678 |
| CAMK2A | phosphorylation up-regulates → | ETS1 PSer251 | phosphorylation down-regulates ⊣ | ETS1 | 12475968 | SIGNOR-96330 |
| CAMK2A | phosphorylation up-regulates → | EGFR PSer1071 | phosphorylation down-regulates ⊣ | EGFR | 10347170 | SIGNOR-250621 |
| CAMK2A | phosphorylation up-regulates → | DLGAP1 PSer356 | phosphorylation down-regulates ⊣ | DLGAP1 | 23143515 | SIGNOR-276429 |
| CAMK2A | phosphorylation up-regulates → | EGFR PSer1070 | phosphorylation down-regulates ⊣ | EGFR | 10347170 | SIGNOR-250620 |
| CAMK2A | phosphorylation up-regulates → | CALD1 PSer643 | phosphorylation down-regulates ⊣ | CALD1 | 2170388 | SIGNOR-22631 |
| CAMK2A | phosphorylation up-regulates → | SMAD2 PSer110 | phosphorylation down-regulates ⊣ | SMAD2 | 11027280 | SIGNOR-82966 |
| CAMK2A | phosphorylation up-regulates → | EGFR PSer1120 | phosphorylation down-regulates ⊣ | EGFR | 10347170 | SIGNOR-250623 |
| CAMK2A | phosphorylation up-regulates → | KRT18 PSer53 | phosphorylation down-regulates ⊣ | KRT18 | 7523419 | SIGNOR-250633 |
| CAMK2A | phosphorylation up-regulates → | CLCN3 PSer109 | phosphorylation up-regulates → | CLCN3 | 14754994 | SIGNOR-275863 |
| CAMK2A | phosphorylation up-regulates → | PDC PSer54 | phosphorylation down-regulates ⊣ | PDC | 11331285 | SIGNOR-250636 |
| CAMK2A | phosphorylation up-regulates → | SYNGAP1 PThr1077 | phosphorylation up-regulates → | SYNGAP1 | 15358237 | SIGNOR-262691 |
| CAMK2A | phosphorylation up-regulates → | SMAD2 PSer240 | phosphorylation down-regulates ⊣ | SMAD2 | 11027280 | SIGNOR-82970 |
| CAMK2A | phosphorylation up-regulates → | NOS1 PSer852 | phosphorylation down-regulates ⊣ | NOS1 | 10400690 | SIGNOR-250635 |
| CAMK2A | phosphorylation up-regulates → | ETS2 PSer310 | phosphorylation down-regulates ⊣ | ETS2 | 19182667 | SIGNOR-183600 |
| CAMK2A | phosphorylation up-regulates → | CYLD PSer362 | phosphorylation up-regulates → | CYLD | 24614225 | SIGNOR-266442 |
| CAMK2A | phosphorylation up-regulates → | HRH1 PSer398 | phosphorylation down-regulates ⊣ | HRH1 | 15107581 | SIGNOR-124344 |
| CAMK2A | phosphorylation up-regulates → | LIPE PSer855 | phosphorylation down-regulates ⊣ | LIPE | 9636039 | SIGNOR-58251 |
| CAMK2A | phosphorylation up-regulates → | GFAP PSer17 | phosphorylation down-regulates ⊣ | GFAP | 7822264 | SIGNOR-250627 |
| CAMK2A | phosphorylation up-regulates → | DLG1 PSer232 | phosphorylation down-regulates ⊣ | DLG1 | 12933808 | SIGNOR-250618 |
| CAMK2A | phosphorylation up-regulates → | SRF PThr160 | phosphorylation up-regulates → | SRF | 10753652 | SIGNOR-250639 |
| CAMK2A | phosphorylation up-regulates → | GRIN2B PSer1303 | phosphorylation up-regulates → | GRIN2B | 8940188 | SIGNOR-250630 |
| CAMK2A | phosphorylation up-regulates → | GFAP PSer13 | phosphorylation down-regulates ⊣ | GFAP | 7822264 | SIGNOR-250626 |
| CAMK2A | phosphorylation up-regulates → | ETS1 PSer257 | phosphorylation down-regulates ⊣ | ETS1 | 12475968 | SIGNOR-96334 |
| CAMK2A | phosphorylation up-regulates → | CYLD PSer362 | phosphorylation up-regulates → | CYLD | 24614225 | SIGNOR-266434 |
| CAMK2A | phosphorylation up-regulates → | DAGLA PSer782 | phosphorylation down-regulates ⊣ | DAGLA | 23502535 | SIGNOR-275539 |
| CAMK2A | phosphorylation up-regulates → | RCHY1 PThr154 | phosphorylation down-regulates ⊣ | RCHY1 | 17568776 | SIGNOR-156068 |
| CAMK2A | phosphorylation up-regulates → | PKD2L1 PThr591 | phosphorylation down-regulates ⊣ | PKD2L1 | 37193065 | SIGNOR-277798 |
| CAMK2A | phosphorylation up-regulates → | FBXO43 PSer192 | phosphorylation up-regulates → | FBXO43 | 16407128 | SIGNOR-260907 |
| CAMK2A | phosphorylation up-regulates → | NOX5 PSer521 | phosphorylation up-regulates → | NOX5 | 21642394 | SIGNOR-276329 |
| CAMK2A | phosphorylation up-regulates → | PTTG1 PThr66 | phosphorylation down-regulates ⊣ | PTTG1 | 24781523 | SIGNOR-276377 |
| CAMK2A | phosphorylation up-regulates → | EGFR PSer1064 | phosphorylation down-regulates ⊣ | EGFR | 10347170 | SIGNOR-250619 |
| CAMK2A | phosphorylation up-regulates → | CAMK2A PThr306 | phosphorylation down-regulates ⊣ | CAMK2A | 1324926 | SIGNOR-17316 |
| CAMK2A | phosphorylation up-regulates → | CAMK2A PThr305 | phosphorylation down-regulates ⊣ | CAMK2A | 1324926 | SIGNOR-17312 |
| CAMK2A | phosphorylation up-regulates → | HOMER3 PSer159 | phosphorylation down-regulates ⊣ | HOMER3 | 18480293 | SIGNOR-262685 |
| CAMK2A | phosphorylation up-regulates → | CHAT PThr574 | phosphorylation up-regulates → | CHAT | 12486117 | SIGNOR-96628 |
| CAMK2A | phosphorylation up-regulates → | CD44 PSer706 | phosphorylation up-regulates → | CD44 | 11463356 | SIGNOR-109502 |
| CAMK2A | phosphorylation up-regulates → | ID1 PSer36 | phosphorylation up-regulates → | ID1 | 29079782 | SIGNOR-277367 |
| CAMK2A | phosphorylation up-regulates → | PTTG1 PSer87 | phosphorylation down-regulates ⊣ | PTTG1 | 24781523 | SIGNOR-276381 |
| CAMK2A | phosphorylation up-regulates → | CREB1 PSer142 | phosphorylation down-regulates ⊣ | CREB1 | 9668047 | SIGNOR-59137 |
| CAMK2A | phosphorylation up-regulates → | PTK2 PSer843 | phosphorylation up-regulates → | PTK2 | 15845548 | SIGNOR-135631 |
| CAMK2A | phosphorylation up-regulates → | LRRC7 PSer1439 | phosphorylation down-regulates ⊣ | LRRC7 | 11160423 | SIGNOR-250634 |
| CAMK2A | phosphorylation up-regulates → | GABBR1 PSer868 | phosphorylation down-regulates ⊣ | GABBR1 | 20643921 | SIGNOR-166846 |
| CAMK2A | phosphorylation up-regulates → | NOX5 PThr540 | phosphorylation down-regulates ⊣ | NOX5 | 21642394 | SIGNOR-276330 |
| CAMK2A | phosphorylation up-regulates → | NOX5 PSer544 | phosphorylation down-regulates ⊣ | NOX5 | 21642394 | SIGNOR-276331 |
| CAMK2A | phosphorylation up-regulates → | ETS1 PSer285 | phosphorylation down-regulates ⊣ | ETS1 | 12475968 | SIGNOR-96342 |
| CAMK2A | phosphorylation up-regulates → | ETS2 PSer246 | phosphorylation down-regulates ⊣ | ETS2 | 19182667 | SIGNOR-183596 |
| CAMK2A | phosphorylation up-regulates → | SCN8A PSer641 | phosphorylation up-regulates → | SCN8A | 32611770 | SIGNOR-275785 |
| CAMK2A | phosphorylation up-regulates → | NCOR2 PSer2426 | phosphorylation down-regulates ⊣ | NCOR2 | 22888005 | SIGNOR-191773 |
| CAMK2A | phosphorylation up-regulates → | SCN8A PSer561 | phosphorylation up-regulates → | SCN8A | 32611770 | SIGNOR-275784 |
| CAMK2A | phosphorylation up-regulates → | GFAP PSer393 | phosphorylation down-regulates ⊣ | GFAP | 7822264 | SIGNOR-250629 |
| CAMK2A | phosphorylation up-regulates → | HOMER3 PSer176 | phosphorylation down-regulates ⊣ | HOMER3 | 18480293 | SIGNOR-262686 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CAMK2A | phosphorylation → up-regulates activity | SCN8A | SIGNOR-275786 |
| CAMK2A | phosphorylation → down-regulates activity | DAGLA | SIGNOR-275540 |
| CAMK2A | phosphorylation → down-regulates activity | CACNA1H | SIGNOR-277871 |
| CAMK2A | phosphorylation![]() down-regulates | CAMK2A | SIGNOR-17308 |
| CAMK2A | phosphorylation![]() down-regulates | STMN1 | SIGNOR-149640 |
| CAMK2A | phosphorylation![]() down-regulates | STMN1 | SIGNOR-59354 |
| CAMK2A | phosphorylation → down-regulates activity | GFAP | SIGNOR-250628 |
| CAMK2A | phosphorylation → down-regulates activity | MAPT | SIGNOR-249316 |
| CAMK2A | phosphorylation![]() down-regulates | ETS1 | SIGNOR-96338 |
| CAMK2A | phosphorylation → down-regulates activity | MAPT | SIGNOR-249315 |
| CAMK2A | phosphorylation → down-regulates activity | HOMER3 | SIGNOR-262684 |
| CAMK2A | phosphorylation![]() down-regulates quantity by destabilization | PTTG1 | SIGNOR-276383 |
| CAMK2A | phosphorylation → up-regulates activity | CACNA1S | SIGNOR-263113 |
| CAMK2A | phosphorylation![]() down-regulates | RCHY1 | SIGNOR-156064 |
| CAMK2A | phosphorylation → up-regulates activity | SYNGAP1 | SIGNOR-262690 |
| CAMK2A | phosphorylation → up-regulates activity | CYLD | SIGNOR-266433 |
| CAMK2A | phosphorylation → unknown | PDC | SIGNOR-250637 |
| CAMK2A | phosphorylation![]() down-regulates quantity by destabilization | PTTG1 | SIGNOR-276382 |
| CAMK2A | phosphorylation → up-regulates | RIMS1 | SIGNOR-103886 |
| CAMK2A | phosphorylation → unknown | NOX5 | SIGNOR-276332 |
| CAMK2A | phosphorylation → up-regulates activity | ATP2A2 | SIGNOR-250616 |
| CAMK2A | phosphorylation → up-regulates | RIMS1 | SIGNOR-103890 |
| CAMK2A | phosphorylation → up-regulates activity | SCN5A | SIGNOR-275771 |
| CAMK2A | phosphorylation → up-regulates activity | SRF | SIGNOR-250638 |
| CAMK2A | phosphorylation![]() down-regulates | ETS2 | SIGNOR-183604 |
| CAMK2A | phosphorylation → up-regulates activity | ALOX5 | SIGNOR-264408 |
| CAMK2A | phosphorylation → up-regulates | ITPKA | SIGNOR-48387 |
| CAMK2A | phosphorylation → up-regulates | GFPT1 | SIGNOR-158486 |
| CAMK2A | phosphorylation → up-regulates | CD44 | SIGNOR-57376 |
| CAMK2A | phosphorylation → up-regulates activity | ITGB1BP1 | SIGNOR-250632 |
| CAMK2A | phosphorylation → unknown | NOX5 | SIGNOR-276333 |
| CAMK2A | phosphorylation → down-regulates activity | ANKS1B | SIGNOR-264231 |
| CAMK2A | phosphorylation → up-regulates activity | CYLD | SIGNOR-266441 |
| CAMK2A | phosphorylation → down-regulates activity | MAPT | SIGNOR-249314 |
| CAMK2A | phosphorylation → up-regulates activity | SYNGAP1 | SIGNOR-262687 |
| CAMK2A | phosphorylation → up-regulates | PEA15 | SIGNOR-137614 |
| CAMK2A | phosphorylation → up-regulates activity | SCN5A | SIGNOR-275770 |
| CAMK2A | phosphorylation → up-regulates activity | SYNGAP1 | SIGNOR-262688 |
| CAMK2A | phosphorylation![]() down-regulates | OPRM1 | SIGNOR-79682 |
| CAMK2A | phosphorylation → up-regulates | GRIA4 | SIGNOR-97546 |
| CAMK2A | phosphorylation![]() down-regulates | CREB1 | SIGNOR-82501 |
| CAMK2A | phosphorylation → up-regulates activity | GLO1 | SIGNOR-273553 |
| CAMK2A | phosphorylation → up-regulates activity | CEBPB | SIGNOR-250617 |
| CAMK2A | phosphorylation → up-regulates | CAMK2A | SIGNOR-21797 |
| CAMK2A | phosphorylation → up-regulates | TH | SIGNOR-20912 |
| CAMK2A | phosphorylation![]() down-regulates | OPRM1 | SIGNOR-79686 |
| CAMK2A | phosphorylation![]() down-regulates | MAPT | SIGNOR-255490 |
| CAMK2A | phosphorylation → down-regulates activity | PKD2L1 | SIGNOR-277812 |
| CAMK2A | phosphorylation → up-regulates activity | HSF1 | SIGNOR-250631 |
| CAMK2A | phosphorylation → up-regulates | AMPA | SIGNOR-270230 |
| CAMK2A | phosphorylation → up-regulates activity | SYNGAP1 | SIGNOR-262689 |
| CAMK2A | phosphorylation![]() down-regulates | CALD1 | SIGNOR-22635 |
| CAMK2A | phosphorylation![]() down-regulates | CREB1 | SIGNOR-117344 |
| CAMK2A | phosphorylation![]() down-regulates | CACNA1B | SIGNOR-149684 |
| CAMK2A | phosphorylation → down-regulates activity | SLN | SIGNOR-264778 |
| CAMK2A | phosphorylation → down-regulates activity | EGFR | SIGNOR-250624 |
| CAMK2A | phosphorylation → down-regulates activity | EGFR | SIGNOR-250625 |
| CAMK2A | phosphorylation → down-regulates activity | EGFR | SIGNOR-250622 |
| CAMK2A | phosphorylation![]() down-regulates | SMAD2 | SIGNOR-82974 |
| CAMK2A | phosphorylation![]() down-regulates | HRH1 | SIGNOR-124348 |
| CAMK2A | phosphorylation → up-regulates activity | SCN5A | SIGNOR-275772 |
| CAMK2A | phosphorylation![]() down-regulates | OPRM1 | SIGNOR-79678 |
| CAMK2A | phosphorylation![]() down-regulates | ETS1 | SIGNOR-96330 |
| CAMK2A | phosphorylation → down-regulates activity | EGFR | SIGNOR-250621 |
| CAMK2A | phosphorylation![]() down-regulates quantity by destabilization | DLGAP1 | SIGNOR-276429 |
| CAMK2A | phosphorylation → down-regulates activity | EGFR | SIGNOR-250620 |
| CAMK2A | phosphorylation![]() down-regulates | CALD1 | SIGNOR-22631 |
| CAMK2A | phosphorylation![]() down-regulates | SMAD2 | SIGNOR-82966 |
| CAMK2A | phosphorylation → down-regulates activity | EGFR | SIGNOR-250623 |
| CAMK2A | phosphorylation → unknown | KRT18 | SIGNOR-250633 |
| CAMK2A | phosphorylation → up-regulates activity | CLCN3 | SIGNOR-275863 |
| CAMK2A | phosphorylation → unknown | PDC | SIGNOR-250636 |
| CAMK2A | phosphorylation → up-regulates activity | SYNGAP1 | SIGNOR-262691 |
| CAMK2A | phosphorylation![]() down-regulates | SMAD2 | SIGNOR-82970 |
| CAMK2A | phosphorylation → down-regulates activity | NOS1 | SIGNOR-250635 |
| CAMK2A | phosphorylation![]() down-regulates | ETS2 | SIGNOR-183600 |
| CAMK2A | phosphorylation → up-regulates activity | CYLD | SIGNOR-266442 |
| CAMK2A | phosphorylation![]() down-regulates | HRH1 | SIGNOR-124344 |
| CAMK2A | phosphorylation![]() down-regulates | LIPE | SIGNOR-58251 |
| CAMK2A | phosphorylation → down-regulates activity | GFAP | SIGNOR-250627 |
| CAMK2A | phosphorylation → down-regulates activity | DLG1 | SIGNOR-250618 |
| CAMK2A | phosphorylation → up-regulates activity | SRF | SIGNOR-250639 |
| CAMK2A | phosphorylation → up-regulates activity | GRIN2B | SIGNOR-250630 |
| CAMK2A | phosphorylation → down-regulates activity | GFAP | SIGNOR-250626 |
| CAMK2A | phosphorylation![]() down-regulates | ETS1 | SIGNOR-96334 |
| CAMK2A | phosphorylation → up-regulates activity | CYLD | SIGNOR-266434 |
| CAMK2A | phosphorylation → down-regulates activity | DAGLA | SIGNOR-275539 |
| CAMK2A | phosphorylation![]() down-regulates | RCHY1 | SIGNOR-156068 |
| CAMK2A | phosphorylation → down-regulates activity | PKD2L1 | SIGNOR-277798 |
| CAMK2A | phosphorylation → up-regulates activity | FBXO43 | SIGNOR-260907 |
| CAMK2A | phosphorylation → up-regulates activity | NOX5 | SIGNOR-276329 |
| CAMK2A | phosphorylation![]() down-regulates quantity by destabilization | PTTG1 | SIGNOR-276377 |
| CAMK2A | phosphorylation → down-regulates activity | EGFR | SIGNOR-250619 |
| CAMK2A | phosphorylation![]() down-regulates | CAMK2A | SIGNOR-17316 |
| CAMK2A | phosphorylation![]() down-regulates | CAMK2A | SIGNOR-17312 |
| CAMK2A | phosphorylation → down-regulates activity | HOMER | SIGNOR-264699 |
| CAMK2A | phosphorylation → down-regulates activity | HOMER3 | SIGNOR-262685 |
| CAMK2A | phosphorylation → up-regulates | CHAT | SIGNOR-96628 |
| CAMK2A | phosphorylation → up-regulates activity | CD44 | SIGNOR-109502 |
| CAMK2A | phosphorylation → up-regulates activity | ID1 | SIGNOR-277367 |
| CAMK2A | phosphorylation![]() down-regulates quantity by destabilization | PTTG1 | SIGNOR-276381 |
| CAMK2A | phosphorylation![]() down-regulates | CREB1 | SIGNOR-59137 |
| CAMK2A | phosphorylation → up-regulates | PTK2 | SIGNOR-135631 |
| CAMK2A | phosphorylation → unknown | LRRC7 | SIGNOR-250634 |
| CAMK2A | phosphorylation![]() down-regulates | GABBR1 | SIGNOR-166846 |
| CAMK2A | phosphorylation → unknown | NOX5 | SIGNOR-276330 |
| CAMK2A | phosphorylation → unknown | NOX5 | SIGNOR-276331 |
| CAMK2A | phosphorylation![]() down-regulates | ETS1 | SIGNOR-96342 |
| CAMK2A | phosphorylation![]() down-regulates | ETS2 | SIGNOR-183596 |
| CAMK2A | phosphorylation → up-regulates activity | SCN8A | SIGNOR-275785 |
| CAMK2A | phosphorylation![]() down-regulates | NCOR2 | SIGNOR-191773 |
| CAMK2A | phosphorylation → up-regulates activity | SCN8A | SIGNOR-275784 |
| CAMK2A | phosphorylation → down-regulates activity | GFAP | SIGNOR-250629 |
| CAMK2A | phosphorylation → down-regulates activity | HOMER3 | SIGNOR-262686 |