| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPM1F | CAMK2A | Thr286 | SCMHRQEtVDCLKKF | dephosphorylation down-regulates | 15140879 | SIGNOR-124309 |
| CAMK2A | CAMK2A | Thr286 | SCMHRQEtVDCLKKF | phosphorylation up-regulates | 1849884 | SIGNOR-21797 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPM1F | dephosphorylation down-regulates ⊣ | CAMK2A PThr286 | dephosphorylation up-regulates → | CAMK2A | 15140879 | SIGNOR-124309 |
| CAMK2A | phosphorylation up-regulates → | CAMK2A PThr286 | phosphorylation up-regulates → | CAMK2A | 1849884 | SIGNOR-21797 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PPM1F | dephosphorylation down-regulates | CAMK2A | SIGNOR-124309 |
| CAMK2A | phosphorylation → up-regulates | CAMK2A | SIGNOR-21797 |
