| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK1 | NINL | Ser185 | NRHSPSWsPDGRRRQ | phosphorylation up-regulates activity | 20890132 | SIGNOR-259830 |
| AURKB | NINL | Ser185 | WDSEDFGsPQKSCSP | phosphorylation up-regulates | 20864540 | SIGNOR-168045 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK1 | phosphorylation up-regulates → | NINL PSer185 | phosphorylation up-regulates → | NINL | 20890132 | SIGNOR-259830 |
| AURKB | phosphorylation up-regulates → | NINL PSer185 | phosphorylation up-regulates → | NINL | 20864540 | SIGNOR-168045 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CDK1 | phosphorylation → up-regulates activity | NINL | SIGNOR-259830 |
| AURKB | phosphorylation → up-regulates | NINL | SIGNOR-168045 |
