Entity Details

Name MAP3K2
ID Q9Y2U5
Role kinase
Enzymatic Domains
PB1 43-122
PROSITE-ProRule
Protein kinase 357-617
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
MAP3K2MAP2K7–phosphorylation
up-regulates activity		25190348SIGNOR-279212
MAP3K2MAP2K4–phosphorylation
up-regulates activity		11343802SIGNOR-107695
MAP3K2PXN–phosphorylation
down-regulates quantity		25190348SIGNOR-278955
MAP3K2MAP2K1–phosphorylation
up-regulates		11343802SIGNOR-107692
MAP3K2MAP2K5–phosphorylation
up-regulates		12912994SIGNOR-104634
MAP3K2STK38Ser91LGLEDFEsLKVIGRGphosphorylation
up-regulates quantity by stabilization		31690749SIGNOR-279066
MAP3K2MEK1/2–phosphorylation
up-regulates		11343802SIGNOR-244888
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
MAP3K2phosphorylation
up-regulates
→
STK38
PSer91		phosphorylation
up-regulates
→		STK3831690749SIGNOR-279066
Regulator Mechanism/Effect Target SIGNOR-ID
MAP3K2phosphorylation
→
up-regulates activity 		MAP2K7SIGNOR-279212
MAP3K2phosphorylation
→
up-regulates activity 		MAP2K4SIGNOR-107695
MAP3K2phosphorylation
→
down-regulates quantity 		PXNSIGNOR-278955
MAP3K2phosphorylation
→
up-regulates 		MAP2K1SIGNOR-107692
MAP3K2phosphorylation
→
up-regulates 		MAP2K5SIGNOR-104634
MAP3K2phosphorylation
→
up-regulates quantity by stabilization 		STK38SIGNOR-279066
MAP3K2phosphorylation
→
up-regulates 		MEK1/2SIGNOR-244888