| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| DYRK2 | CARHSP1 | Ser32 | RSRERSPsPLRGNVV | phosphorylation unknown | 15910284 | SIGNOR-137478 |
| DYRK2 | CARHSP1 | Ser30 | TPRSRERsPSPLRGN | phosphorylation unknown | 15910284 | SIGNOR-137474 |
| AKT | CARHSP1 | Ser52 | TRRTRTFsATVRASQ | phosphorylation unknown | 15910284 | SIGNOR-137430 |
| DYRK2 | CARHSP1 | Ser41 | LRGNVVPsPLPTRRT | phosphorylation unknown | 21177848 | SIGNOR-170781 |
| RPS6K | CARHSP1 | Ser52 | TRRTRTFsATVRASQ | phosphorylation unknown | 15910284 | SIGNOR-252814 |
| RPS6KA1 | CARHSP1 | Ser52 | TRRTRTFsATVRASQ | phosphorylation unknown | 15910284 | SIGNOR-137482 |
| AKT1 | CARHSP1 | Ser52 | TRRTRTFsATVRASQ | phosphorylation unknown | 15910284 | SIGNOR-252478 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| DYRK2 | phosphorylation up-regulates → | CARHSP1 PSer32 | phosphorylation down-regulates ⊣ | CARHSP1 | 15910284 | SIGNOR-137478 |
| DYRK2 | phosphorylation up-regulates → | CARHSP1 PSer30 | phosphorylation down-regulates ⊣ | CARHSP1 | 15910284 | SIGNOR-137474 |
| AKT | phosphorylation up-regulates → | CARHSP1 PSer52 | phosphorylation down-regulates ⊣ | CARHSP1 | 15910284 | SIGNOR-137430 |
| DYRK2 | phosphorylation up-regulates → | CARHSP1 PSer41 | phosphorylation down-regulates ⊣ | CARHSP1 | 21177848 | SIGNOR-170781 |
| RPS6K | phosphorylation up-regulates → | CARHSP1 PSer52 | phosphorylation down-regulates ⊣ | CARHSP1 | 15910284 | SIGNOR-252814 |
| RPS6KA1 | phosphorylation up-regulates → | CARHSP1 PSer52 | phosphorylation down-regulates ⊣ | CARHSP1 | 15910284 | SIGNOR-137482 |
| AKT1 | phosphorylation up-regulates → | CARHSP1 PSer52 | phosphorylation down-regulates ⊣ | CARHSP1 | 15910284 | SIGNOR-252478 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| DYRK2 | phosphorylation → unknown | CARHSP1 | SIGNOR-137478 |
| DYRK2 | phosphorylation → unknown | CARHSP1 | SIGNOR-137474 |
| AKT | phosphorylation → unknown | CARHSP1 | SIGNOR-137430 |
| DYRK2 | phosphorylation → unknown | CARHSP1 | SIGNOR-170781 |
| RPS6K | phosphorylation → unknown | CARHSP1 | SIGNOR-252814 |
| RPS6KA1 | phosphorylation → unknown | CARHSP1 | SIGNOR-137482 |
| AKT1 | phosphorylation → unknown | CARHSP1 | SIGNOR-252478 |
