| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AKT1 | RNF11 | Thr135 | DWLMRSFtCPSCMEP | phosphorylation down-regulates quantity | 16123141 | SIGNOR-252558 |
| AKT | RNF11 | Thr135 | DWLMRSFtCPSCMEP | phosphorylation down-regulates quantity | 16123141 | SIGNOR-248085 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AKT1 | phosphorylation up-regulates → | RNF11 PThr135 | phosphorylation down-regulates ⊣ | RNF11 | 16123141 | SIGNOR-252558 |
| AKT | phosphorylation up-regulates → | RNF11 PThr135 | phosphorylation down-regulates ⊣ | RNF11 | 16123141 | SIGNOR-248085 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| AKT1 | phosphorylation → down-regulates quantity | RNF11 | SIGNOR-252558 |
| AKT | phosphorylation → down-regulates quantity | RNF11 | SIGNOR-248085 |