| Name | SAMHD1 |
| ID | Q9Y3Z3 |
| Role | substrate |
| Enzymatic Domains |
SAM 45-110 PROSITE-ProRule
HD 164-316 PROSITE-ProRule |
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|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK1 | SAMHD1 | Thr592 | DVIAPLItPQKKEWN | phosphorylation down-regulates | 23602554 | SIGNOR-201913 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK1 | phosphorylation up-regulates → | SAMHD1 PThr592 | phosphorylation down-regulates ⊣ | SAMHD1 | 23602554 | SIGNOR-201913 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CDK1 | phosphorylation down-regulates | SAMHD1 | SIGNOR-201913 |