| Name | DYRK1B |
| ID | Q9Y463 |
| Role | substrate |
| Enzymatic Domains |
Protein kinase 111-431 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| DYRK1B | DYRK1B | Tyr273 | LGQRIYQyIQSRFYR | phosphorylation up-regulates | 10910078 | SIGNOR-79810 |
| DYRK1B | DYRK1B | Tyr271 | CQLGQRIyQYIQSRF | phosphorylation up-regulates | 10910078 | SIGNOR-79806 |
| MAPK1 | DYRK1B | Ser421 | YEPAARIsPLGALQH | phosphorylation up-regulates activity | 26346493 | SIGNOR-276937 |
| MAP2K3 | DYRK1B | – | phosphorylation up-regulates | 11980910 | SIGNOR-86731 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| DYRK1B | phosphorylation up-regulates → | DYRK1B PTyr273 | phosphorylation up-regulates → | DYRK1B | 10910078 | SIGNOR-79810 |
| DYRK1B | phosphorylation up-regulates → | DYRK1B PTyr271 | phosphorylation up-regulates → | DYRK1B | 10910078 | SIGNOR-79806 |
| MAPK1 | phosphorylation up-regulates → | DYRK1B PSer421 | phosphorylation up-regulates → | DYRK1B | 26346493 | SIGNOR-276937 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| DYRK1B | phosphorylation → up-regulates | DYRK1B | SIGNOR-79810 |
| DYRK1B | phosphorylation → up-regulates | DYRK1B | SIGNOR-79806 |
| MAPK1 | phosphorylation → up-regulates activity | DYRK1B | SIGNOR-276937 |
| MAP2K3 | phosphorylation → up-regulates | DYRK1B | SIGNOR-86731 |