| Name | MAP4K5 |
| ID | Q9Y4K4 |
| Role | kinase |
| Enzymatic Domains |
Protein kinase 20-277 PROSITE-ProRule
CNH 506-819 PROSITE-ProRule |
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|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAP4K5 | GSK3B | Ser9 | SGRPRTTsFAESCKP | phosphorylation down-regulates | 16914735 | SIGNOR-148908 |
| MAP4K5 | GSK3B/Axin/APC | – | phosphorylation down-regulates activity | 16914735 | SIGNOR-228006 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAP4K5 | phosphorylation up-regulates → | GSK3B PSer9 | phosphorylation down-regulates ⊣ | GSK3B | 16914735 | SIGNOR-148908 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAP4K5 | phosphorylation down-regulates | GSK3B | SIGNOR-148908 |
| MAP4K5 | phosphorylation → down-regulates activity | GSK3B/Axin/APC | SIGNOR-228006 |