| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CAMK1 | PPME1 | Ser15 | MHLGRLPsRPPLPGS | phosphorylation up-regulates activity | 24841198 | SIGNOR-276636 |
| CAMK1 | PPME1 | Ser15 | MHLGRLPsRPPLPGS | phosphorylation down-regulates activity | 24841198 | SIGNOR-265747 |
| PP2CA_R1A_R2A | PPME1 | Ser15 | MHLGRLPsRPPLPGS | dephosphorylation up-regulates activity | 24841198 | SIGNOR-265752 |
| CAMK1 | PPME1 | Ser15 | MHLGRLPsRPPLPGS | phosphorylation up-regulates activity | 24841198 | SIGNOR-277827 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CAMK1 | phosphorylation up-regulates → | PPME1 PSer15 | phosphorylation up-regulates → | PPME1 | 24841198 | SIGNOR-276636 |
| CAMK1 | phosphorylation up-regulates → | PPME1 PSer15 | phosphorylation down-regulates ⊣ | PPME1 | 24841198 | SIGNOR-265747 |
| PP2CA_R1A_R2A | dephosphorylation down-regulates ⊣ | PPME1 PSer15 | dephosphorylation down-regulates ⊣ | PPME1 | 24841198 | SIGNOR-265752 |
| CAMK1 | phosphorylation up-regulates → | PPME1 PSer15 | phosphorylation up-regulates → | PPME1 | 24841198 | SIGNOR-277827 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CAMK1 | phosphorylation → up-regulates activity | PPME1 | SIGNOR-276636 |
| CAMK1 | phosphorylation → down-regulates activity | PPME1 | SIGNOR-265747 |
| PP2CA_R1A_R2A | dephosphorylation → up-regulates activity | PPME1 | SIGNOR-265752 |
| CAMK1 | phosphorylation → up-regulates activity | PPME1 | SIGNOR-277827 |