| Name | SNX8 |
| ID | Q9Y5X2 |
| Role | substrate |
| Enzymatic Domains |
PX 73-181 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| JAK1 | SNX8 | Tyr95 | LFLKHVEyEVSSQRF | phosphorylation up-regulates activity | 29180417 | SIGNOR-273647 |
| JAK1 | SNX8 | Tyr126 | MLLHKFPyRMVPALP | phosphorylation up-regulates activity | 29180417 | SIGNOR-273645 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| JAK1 | phosphorylation up-regulates → | SNX8 PTyr95 | phosphorylation up-regulates → | SNX8 | 29180417 | SIGNOR-273647 |
| JAK1 | phosphorylation up-regulates → | SNX8 PTyr126 | phosphorylation up-regulates → | SNX8 | 29180417 | SIGNOR-273645 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| JAK1 | phosphorylation → up-regulates activity | SNX8 | SIGNOR-273647 |
| JAK1 | phosphorylation → up-regulates activity | SNX8 | SIGNOR-273645 |