| Name | FHOD1 |
| ID | Q9Y613 |
| Role | substrate |
| Enzymatic Domains |
GBD/FH3 53-458 PROSITE-ProRule
FH1 487-615
FH2 616-1013 PROSITE-ProRule
DAD 1053-1133 |
View in  |
|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SRC | FHOD1 | Tyr99 | REMLEGFyEEISKGR | phosphorylation up-regulates activity | 24331927 | SIGNOR-276612 |
| ROCK1 | FHOD1 | Ser1137 | RSRGNRKsLRRTLKS | phosphorylation up-regulates | 18239683 | SIGNOR-160548 |
| PRKG1 | FHOD1 | Ser1131 | AARERKRsRGNRKSL | phosphorylation up-regulates | 15051728 | SIGNOR-123646 |
| ROCK1 | FHOD1 | Ser1131 | AARERKRsRGNRKSL | phosphorylation up-regulates | 18239683 | SIGNOR-160544 |
| PRKG1 | FHOD1 | Ser1131 | AARERKRsRGNRKSL | phosphorylation up-regulates | 21106951 | SIGNOR-170094 |
| ROCK1 | FHOD1 | Thr1141 | NRKSLRRtLKSGLGD | phosphorylation up-regulates | 18239683 | SIGNOR-160552 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SRC | phosphorylation up-regulates → | FHOD1 PTyr99 | phosphorylation up-regulates → | FHOD1 | 24331927 | SIGNOR-276612 |
| ROCK1 | phosphorylation up-regulates → | FHOD1 PSer1137 | phosphorylation up-regulates → | FHOD1 | 18239683 | SIGNOR-160548 |
| PRKG1 | phosphorylation up-regulates → | FHOD1 PSer1131 | phosphorylation up-regulates → | FHOD1 | 15051728 | SIGNOR-123646 |
| ROCK1 | phosphorylation up-regulates → | FHOD1 PSer1131 | phosphorylation up-regulates → | FHOD1 | 18239683 | SIGNOR-160544 |
| PRKG1 | phosphorylation up-regulates → | FHOD1 PSer1131 | phosphorylation up-regulates → | FHOD1 | 21106951 | SIGNOR-170094 |
| ROCK1 | phosphorylation up-regulates → | FHOD1 PThr1141 | phosphorylation up-regulates → | FHOD1 | 18239683 | SIGNOR-160552 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| SRC | phosphorylation → up-regulates activity | FHOD1 | SIGNOR-276612 |
| ROCK1 | phosphorylation → up-regulates | FHOD1 | SIGNOR-160548 |
| PRKG1 | phosphorylation → up-regulates | FHOD1 | SIGNOR-123646 |
| ROCK1 | phosphorylation → up-regulates | FHOD1 | SIGNOR-160544 |
| PRKG1 | phosphorylation → up-regulates | FHOD1 | SIGNOR-170094 |
| ROCK1 | phosphorylation → up-regulates | FHOD1 | SIGNOR-160552 |