| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PFKFB4 | NCOA3 | Ser857 | PPYNRAVsLDSPVSV | phosphorylation up-regulates activity | 29615789 | SIGNOR-267269 |
| MAPK6 | NCOA3 | Ser857 | PPYNRAVsLDSPVSV | phosphorylation up-regulates | 22505454 | SIGNOR-196957 |
| CHUK | NCOA3 | Ser857 | PPYNRAVsLDSPVSV | phosphorylation up-regulates | 15383283 | SIGNOR-127064 |
| PRKACA | NCOA3 | Ser857 | PPYNRAVsLDSPVSV | phosphorylation up-regulates | 15383283 | SIGNOR-129349 |
| CHUK | NCOA3 | Ser857 | PPYNRAVsLDSPVSV | phosphorylation up-regulates | 22505454 | SIGNOR-196953 |
| PRKACA | NCOA3 | Ser857 | PPYNRAVsLDSPVSV | phosphorylation up-regulates | 22505454 | SIGNOR-196961 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PFKFB4 | phosphorylation up-regulates → | NCOA3 PSer857 | phosphorylation up-regulates → | NCOA3 | 29615789 | SIGNOR-267269 |
| MAPK6 | phosphorylation up-regulates → | NCOA3 PSer857 | phosphorylation up-regulates → | NCOA3 | 22505454 | SIGNOR-196957 |
| CHUK | phosphorylation up-regulates → | NCOA3 PSer857 | phosphorylation up-regulates → | NCOA3 | 15383283 | SIGNOR-127064 |
| PRKACA | phosphorylation up-regulates → | NCOA3 PSer857 | phosphorylation up-regulates → | NCOA3 | 15383283 | SIGNOR-129349 |
| CHUK | phosphorylation up-regulates → | NCOA3 PSer857 | phosphorylation up-regulates → | NCOA3 | 22505454 | SIGNOR-196953 |
| PRKACA | phosphorylation up-regulates → | NCOA3 PSer857 | phosphorylation up-regulates → | NCOA3 | 22505454 | SIGNOR-196961 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PFKFB4 | phosphorylation → up-regulates activity | NCOA3 | SIGNOR-267269 |
| MAPK6 | phosphorylation → up-regulates | NCOA3 | SIGNOR-196957 |
| CHUK | phosphorylation → up-regulates | NCOA3 | SIGNOR-127064 |
| PRKACA | phosphorylation → up-regulates | NCOA3 | SIGNOR-129349 |
| CHUK | phosphorylation → up-regulates | NCOA3 | SIGNOR-196953 |
| PRKACA | phosphorylation → up-regulates | NCOA3 | SIGNOR-196961 |
